Multi-omics approaches to disease
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Summary
This review provides an overview of omics technologies and methods for their integration across multiple omics layers and offers the opportunity to understand the flow of information that underlies disease.
- Type
- review
- Published
- 2017-05-05
- Cited by
- 2,420
- References
- 182
- Access
- Open access
- OpenAlex
- https://openalex.org/W2611138580
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:206983772
Keywords
Genome Biology, Biology, Human genetics, Omics, Computational biology
References
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- Unraveling the environmental and genetic interactions in atherosclerosis: Central role of the gut microbiota
- The Genotype-Tissue Expression (GTEx) project
- FTO Obesity Variant Circuitry and Adipocyte Browning in Humans
- Single-cell messenger RNA sequencing reveals rare intestinal cell types
- Networks: An Introduction
- How data analysis affects power, reproducibility and biological insight of RNA-seq studies in complex datasets
- Eigengene networks for studying the relationships between co-expression modules
- Genetic Control of Obesity and Gut Microbiota Composition in Response to High-Fat, High-Sucrose Diet in Mice
- The landscape of genetic complexity across 5,700 gene expression traits in yeast.
- Mass spectrometry-based metabolomics.
- The Architecture of Gene Regulatory Variation across Multiple Human Tissues: The MuTHER Study
- Integrating Genetic and Network Analysis to Characterize Genes Related to Mouse Weight
- Targeted Capture and Massively Parallel Sequencing of Twelve Human Exomes
- DNA methylation age of human tissues and cell types
- A large-scale method to measure absolute protein phosphorylation stoichiometries
- JOINT ANALYSIS OF SNP AND GENE EXPRESSION DATA IN GENETIC ASSOCIATION STUDIES OF COMPLEX DISEASES
Cited by
- Metabolomics study of the hepatoprotective effect of Phellinus igniarius in chronic ethanol-induced liver injury mice using UPLC-Q/TOF-MS combined with ingenuity pathway analysis.
- A Primer on Data Analytics in Functional Genomics: How to Move from Data to Insight?
- Multiomics-based strategies for taming intestinal inflammation in the neonate
- Big science and big data in nephrology.
- Bardet-Biedl syndrome
- The transformative potential of an integrative approach to pregnancy.
- Mass-spectrometry-based lipidomics.
- Precision Oncology: The Promise of Big Data and the Legacy of Small Data
- Using omics to explore complications of kidney transplantation
- Mini-Review: The Contribution of Intermediate Phenotypes to GxE Effects on Disorders of Body Composition in the New OMICS Era
- Mediterranean Diet and Multi-Ingredient-Based Interventions for the Management of Non-Alcoholic Fatty Liver Disease
- Multi-omics analysis reveals that ornithine decarboxylase contributes to erlotinib resistance in pancreatic cancer cells
- Can we Understand the Pathobiology of Bronchopulmonary Dysplasia??
- Gender-related metabolomics and lipidomics: From experimental animal models to clinical evidence.
- Integrative Analysis of Proteomics Data to Obtain Clinically Relevant Markers.
- Comparative transcriptomic analysis of human placentae at term and preterm delivery
- Voluntary Exposure to a Toxin: the Genetic Influence on Ethanol Consumption
- Brief guide to the analysis, interpretation and presentation of microbiota data
- Biological Systems as Heterogeneous Information Networks: A Mini-review and Perspectives
- Food allergy and omics.
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