FOXM1 binds directly to non-consensus sequences in the human genome
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Summary
Analysis of the protein interactome of wild-type versus DNA binding deficient FOXM1 shows that the reduced recruitment is not due to inhibition of protein-protein interactions, suggesting a functional DNA binding domain is essential forFOXM1 chromatin recruitment.
- Type
- article
- Published
- 2015-06-23
- Cited by
- 63
- References
- 80
- Access
- Open access
- OpenAlex
- https://openalex.org/W1568433819
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:179088
Keywords
Biology, Genome Biology, Human genetics, Genetics, Genome
References
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- REVIGO Summarizes and Visualizes Long Lists of Gene Ontology Terms
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- Co-crystal structure of the HNF-3/fork head DNA-recognition motif resembles histone H5
Cited by
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- Rapid immunoprecipitation mass spectrometry of endogenous proteins (RIME) for analysis of chromatin complexes
- The Forkhead box transcription factor FOXM1 is required for the maintenance of cell proliferation and protection against oxidative stress in human embryonic stem cells.
- HGF/Met and FOXM1 Form a Positive Feedback Loop and Render Pancreatic Cancer Cells Resistance to Met Inhibition and Aggressive Phenotypes
- Timing of transcription during the cell cycle: Protein complexes binding to E2F, E2F/CLE, CDE/CHR, or CHR promoter elements define early and late cell cycle gene expression
- Thyroid transcription factor FOXE1 interacts with ETS factor ELK1 to co-regulate TERT
- The FOXP2 forkhead domain binds to a variety of DNA sequences with different rates and affinities
- The FOXM1–ABCC5 axis contributes to paclitaxel resistance in nasopharyngeal carcinoma cells
- VprBP/DCAF1 Regulates the Degradation and Nonproteolytic Activation of the Cell Cycle Transcription Factor FoxM1
- The epigenetic integrator UHRF1: on the road to become a universal biomarker for cancer
- Cell cycle transcription control: DREAM/MuvB and RB-E2F complexes
- Cancer cell line specific co-factors modulate the FOXM1 cistrome
- Cell cycle arrest through indirect transcriptional repression by p53: I have a DREAM
- FOXM1 promotes pulmonary artery smooth muscle cell expansion in pulmonary arterial hypertension
- Target gene regulation by EBV latent transcription factors - exploiting cellular enhancer elements
- FOXM1 promotes proliferation in human hepatocellular carcinoma cells by transcriptional activation of CCNB1.
- FOXM1 Expression and Contribution to Genomic Instability and Chemoresistance in High-Grade Serous Ovarian Cancer
- CDK4/6 Inhibitor as a Novel Therapeutic Approach for Advanced Bladder Cancer Independently of RB1 Status
- Epigenetic mechanism and target therapy of UHRF1 protein complex in malignancies
- FOXM1 modulates 5-FU resistance in colorectal cancer through regulating TYMS expression