Voluntary Exposure to a Toxin: the Genetic Influence on Ethanol Consumption
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Summary
It is proposed that these liver secretory products can interact with brain mechanisms that affect alcohol consumption, and targeting these pathways provides a potential approach to reducing high levels of alcohol intake and also protecting the integrity of the liver and other organs.
- Type
- article
- Published
- 2017-12-01
- Cited by
- 10
- References
- 82
- Access
- Open access
- OpenAlex
- https://openalex.org/W2772927733
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:3855455
Keywords
Quantitative trait locus, Biology, Phenotype, Genetics, Gene
References
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- Neuroimmune Pathways in Alcohol Consumption: Evidence from Behavioral and Genetic Studies in Rodents and Humans
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- Genomic landscape of rat strain and substrain variation
- Interleukin‐8: A critical chemokine in biliary atresia
- The nature and identification of quantitative trait loci: a community's view
- Formation of bradykinin: a major contributor to the innate inflammatory response.
- Recent insights into Groucho co-repressor recruitment and function
- The sequenced rat brain transcriptome, its use in identifying networks predisposing alcohol consumption
- Bradykinin suppresses alcohol intake and plays a role in the suppression produced by an ACE inhibitor.
- Influence of Sex on Genetic Regulation of “Drinking in the Dark” Alcohol Consumption
- Role of Appetite-Regulating Peptides in the Pathophysiology of Addiction: Implications for Pharmacotherapy
- Genetic dissection of complex traits: guidelines for interpreting and reporting linkage results
- Endocrine regulation of mitochondrial activity: involvement of truncated RXRα and c‐Erb Aαl proteins
- Liver-brain interactions in inflammatory liver diseases: implications for fatigue and mood disorders.
- The role of regulatory variation in complex traits and disease
- Cytochromes P450 are essential players in the vitamin D signaling system.
- RSEM: accurate transcript quantification from RNA-Seq data with or without a reference genome
- Endocannabinoid signaling via cannabinoid receptor 1 is involved in ethanol preference and its age-dependent decline in mice
Cited by
- Integrating Genetic and Gene Co-expression Analysis Identifies Gene Networks Involved in Alcohol and Stress Responses
- Networking in Biology: The Hybrid Rat Diversity Panel.
- Genome-Wide Systems Genetics of Alcohol Consumption and Dependence
- Alcohol Sensitivity as an Endophenotype of Alcohol Use Disorder: Exploring Its Translational Utility between Rodents and Humans
- Genome-to-phenome research in rats: progress and perspectives
- Aptardi predicts polyadenylation sites in sample-specific transcriptomes using high-throughput RNA sequencing and DNA sequence
- The genetical genomic path to understanding why rats and humans consume too much alcohol
- Liver molecular networks associated with drinking behavior in nonhuman primates
- Introduction to Mammalian Genome Special Issue: The Combined Role of Genetics and Environment Relevant to Human Disease Outcomes
- Integrating Biology With Rat Genomic Tools
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