Metabolites produced by commensal bacteria promote peripheral regulatory T cell generation
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Summary
The results suggest that bacterial metabolites mediate communication between the commensal microbiota and the immune system, affecting the balance between pro- and anti-inflammatory mechanisms.
- Type
- article
- Published
- 2013-11-13
- Cited by
- 4,386
- References
- 27
- Access
- Open access
- OpenAlex
- https://openalex.org/W2003342633
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:4383078
Keywords
Butyrate, Biology, Immune system, FOXP3, Cell biology
References
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- GPR109A is a G-protein-coupled receptor for the bacterial fermentation product butyrate and functions as a tumor suppressor in colon
- Regulatory T cells prevent catastrophic autoimmunity throughout the lifespan of mice
Cited by
- Regulation of regulatory T cells: epigenetics and plasticity.
- Impact of dietary deviation on disease progression and gut microbiome composition in lupus‐prone SNF1 mice
- Mango Supplementation Modulates Gut Microbial Dysbiosis and Short-Chain Fatty Acid Production Independent of Body Weight Reduction in C57BL/6 Mice Fed a High-Fat Diet.
- Interleukin-15 promotes intestinal dysbiosis with butyrate deficiency associated with increased susceptibility to colitis
- Histone Posttranslational Modifications of CD4+ T Cell in Autoimmune Diseases
- Nutrient sensing, signal transduction and immune responses.
- Enteral High Fat-Polyunsaturated Fatty Acid Blend Alters the Pathogen Composition of the Intestinal Microbiome in Premature Infants with an Enterostomy
- The respiratory tract microbiome and lung inflammation: a two-way street
- The microbiome and hepatobiliary-pancreatic cancers.
- Towards an Integrative Understanding of Diet–Host–Gut Microbiome Interactions
- A Common Mechanism Links Activities of Butyrate in the Colon.
- Administration of bifidobacterium and lactobacillus strains modulates experimental myasthenia gravis and experimental encephalomyelitis in Lewis rats
- Sodium Butyrate Mitigates iE-DAP Induced Inflammation Caused by High-Concentrate Feeding in Liver of Dairy Goats.
- Fecal microbiota transplantation: a promising strategy in preventing the progression of non-alcoholic steatohepatitis and improving the anti-cancer immune response
- The Gut Microbiota and Dysbiosis in Autism Spectrum Disorders
- Subcellular antigen localization in commensal E. coli is critical for T cell activation and induction of specific tolerance
- Effects of a vinegar-based multi-micronutrient supplement in rats: a multi-pronged assessment of dietary impact
- Can the Cecal Ligation and Puncture Model Be Repurposed To Better Inform Therapy in Human Sepsis?
- Treg-associated monogenic autoimmune disorders and gut microbial dysbiosis
- Study on the effect of different concentrations of choline glycine ionic liquid-water mixtures on debranched starch butyrylation reaction.
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