Identification of a free fatty acid receptor, FFA2R, expressed on leukocytes and activated by short-chain fatty acids.
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Summary
The human gene to be predominantly expressed in peripheral blood leukocytes and, to a lesser extent, in spleen is found, and the designation FFA(2)R is suggested to be given to this second receptor activated by free fatty acids.
- Type
- article
- Published
- 2003-04-18
- Cited by
- 533
- References
- 28
- OpenAlex
- https://openalex.org/W1972691065
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:22297756
Keywords
Fatty acid, Free fatty acid receptor, Biochemistry, Identification (biology), Chemistry
References
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- A soluble Bacteroides by-product impairs phagocytic killing of Escherichia coli by neutrophils
Cited by
- Short-chain fatty acid signaling pathways in bovine mammary epithelial cells.
- A review of the potential mechanisms for the lowering of colorectal oncogenesis by butyrate
- Omega-3 and omega-6 PUFAs induce the same GPR120-mediated signalling events, but with different kinetics and intensity in Caco-2 cells
- Selective novel inverse agonists for human GPR43 augment GLP-1 secretion.
- Key Questions for Translation of FFA Receptors: From Pharmacology to Medicines.
- Nouveaux concepts dans la pharmacologie des récepteurs aux acides gras à chaîne courte FFA2 et FFA3
- Butyrate-Induced Expression of Proglucagon: Implications for Enteroendocrine Signaling and Intestinal Growth
- INFLUENCE OF DIETARY FIBERS AND WHOLE GRAINS ON FECAL MICROBIOTA DURING IN VITRO FERMENTATION
- The emerging role of promiscuous 7TM receptors as chemosensors for food intake.
- Intestinal sensing of nutrients.
- Free fatty acid receptors and their role in regulation of energy metabolism.
- The role of short chain fatty acids in appetite regulation and energy homeostasis
- Effects of nutrition on development of immune competence in chicken's gut-associated lymphoid system.
- Obesity and prostate cancer: epidemiology, genetics and molecular and cellular mechanisms
- The role of polyunsaturated fatty acids and GPR40 receptor in brain.
- Fermentable carbohydrate intake and differences in health parameters in US college students
- Modulation of the human gut microbiome in order to promote host health and well-being
- Bladder afferent sensitivity in wild‐type and TRPV1 knockout mice
- Drugs or diet? – Developing novel therapeutic strategies targeting the free fatty acid family of GPCRs
- Pharmacological characterisation of the fatty acid receptors GPR120 and FFA1
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