Control of RelB during dendritic cell activation integrates canonical and non-canonical NF-κB pathways

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Summary

It is reported that RelB promoted DC activation not as the expected RelB-p52 effector of the noncanonical NF-κB pathway, but as a Rel B-p50 dimer regulated by canonical IκBs, IκBα andIκBɛ.

Type
article
Published
2012-10-21
Cited by
192
References
62
Access
Open access

Keywords

RELB, Cell biology, NF-κB, Signal transduction, Jurkat cells

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