Can the Cecal Ligation and Puncture Model Be Repurposed To Better Inform Therapy in Human Sepsis?
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Summary
The mouse microbiome of the CLP model is compared and contrast to the emerging science of the microbiome of human sepsis and the relevance for mice to harbor the specific pathogens present in the human microbiome during seps Is discussed, as well as an underlying disease process to mimic the characteristics of patients with undesirable outcomes.
- Type
- article
- Published
- 2020-06-22
- Cited by
- 66
- References
- 81
- OpenAlex
- https://openalex.org/W32571986
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:219986920
Keywords
Session (web analytics), Stage (stratigraphy), Psychology, Business, Advertising
References
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Cited by
- A comprehensive assessment of multi-system responses to a renal inoculation of uropathogenic E. coli in swine
- Imbalanced Subthreshold Currents Following Sepsis and Chemotherapy: A Shared Mechanism Offering a New Therapeutic Target?
- New Approaches to Identify Sepsis Biomarkers: The Importance of Model and Sample Source for Mass Spectrometry
- Probiotics for the Management of Sepsis: Advances in Animal Models and Intensive Care Unit Environments
- Mouse Model of Critical Persistent Inflammation, Immunosuppression, and Catabolism Syndrome
- Metformin attenuates sepsis-induced neuronal injury and cognitive impairment
- Circular RNA VMA21 ameliorates lung injury in septic rat via targeting microRNA-497-5p/CD2-associated protein axis
- Experimental models of acute kidney injury for translational research
- Regulatory T Cells: Angels or Demons in the Pathophysiology of Sepsis?
- Current Understanding of Long-Term Cognitive Impairment After Sepsis
- Dexpanthenol attenuates inflammatory damage and apoptosis in kidney and liver tissues of septic mice
- Surfactant Protein D Influences Mortality During Abdominal Sepsis by Facilitating Escherichia coli Colonization in the Gut
- Panax notoginseng Alleviates Sepsis-Induced Acute Kidney Injury by Reducing Inflammation in Rats
- Of mice and men: Laboratory murine models for recapitulating the immunosuppression of human sepsis
- Complications following transcutaneous cecal trocarization in horses with a cattle trocar and a cecal needle
- Parthenolide Attenuates Sepsis-Induced Acute Kidney Injury in Rats by Reducing Inflammation
- Modeling sepsis, with a special focus on large animal models of porcine peritonitis and bacteremia
- Sulfide-modified nanoscale zero-valent iron as a novel therapeutic remedy for septic myocardial injury
- Dose-specific efficacy of adipose-derived mesenchymal stem cells in septic mice
- Circular RNA protein tyrosine kinase 2 aggravates pyroptosis and inflammation in septic lung tissue by promoting microRNA-766/eukaryotic initiation factor 5A axis-mediated ATP efflux
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