Cellular senescence: from physiology to pathology
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Summary
In cancer and during active tissue repair, pro-senescent therapies contribute to minimize the damage by limiting proliferation and fibrosis, respectively, and antisenescent therapies may help to eliminate accumulated senescent cells and to recover tissue function.
- Type
- review
- Published
- 2014-06-23
- Cited by
- 2,547
- References
- 200
- OpenAlex
- https://openalex.org/W1982481909
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:20062510
Keywords
Senescence, Regeneration (biology), Cell biology, Biology, Cellular senescence
References
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Cited by
- MicroRNAs and lncRNAs in senescence: A re‐view
- Noncoding Transcriptional Landscape in Human Aging.
- Aging in the Canine Kidney
- Melatonin regulates PARP1 to control the senescence‐associated secretory phenotype (SASP) in human fetal lung fibroblast cells
- Gut flora-dependent metabolite Trimethylamine-N-oxide accelerates endothelial cell senescence and vascular aging through oxidative stress.
- Osteogenic protein-1 attenuates the inflammatory cytokine-induced NP cell senescence through regulating the ROS/NF-κB pathway.
- Dexamethasone Induces a Specific Form of Ramified Dysfunctional Microglia
- The Clearance Effect of Tetrahedral DNA Nanostructures on Senescent Human Dermal Fibroblasts.
- p53-suppressed oncogene TET1 prevents cellular aging in lung cancer
- Human skin aging is associated with increased expression of the histone variant H2A.J in the epidermis
- Chemical Strategies for the Detection and Elimination of Senescent Cells
- A Model for p38MAPK-Induced Astrocyte Senescence
- Telomere Dysfunction and Cell Senescence in Chronic Lung Diseases: Therapeutic Potential.
- The DNA damage response and immune signaling alliance: Is it good or bad? Nature decides when and where.
- La semicarbazide-sensitive amine oxydase : son rôle dans la différenciation cellulaire des chondrocytes et des cellules musculaires lisses vasculaires et son implication dans des pathologies articulaires et cardiovasculaires
- Targeting Mdmx to treat breast cancers with wild-type p53
- Telomere Length and Distribution in Three Developmental Stages
- BI2536--A PLK inhibitor augments paclitaxel efficacy in suppressing tamoxifen induced senescence and resistance in breast cancer cells.
- Unexpected role of CDK4 in a G2/M checkpoint
- Autophagy and Cellular Senescence in Lung Diseases
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