The Clearance Effect of Tetrahedral DNA Nanostructures on Senescent Human Dermal Fibroblasts.
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Summary
Tetrahedral DNA nanostructures can induce phenotypic changes in senescent cells, suppressing antiapoptotic BCL-2 family proteins and upregulating BAX to influence the expression levels and function of downstream proteins.
- Type
- article
- Published
- 2019-01-16
- Cited by
- 43
- References
- 41
- OpenAlex
- https://openalex.org/W30562007
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:56478219
Keywords
Josephson effect, Chaotic, Physics, Far infrared, Statistical physics
References
- The Bcl-2 family: roles in cell survival and oncogenesis
- Senescence-Associated Secretory Phenotypes Reveal Cell-Nonautonomous Functions of Oncogenic RAS and the p53 Tumor Suppressor
- JAK inhibition alleviates the cellular senescence-associated secretory phenotype and frailty in old age
- Self-assembly of DNA into nanoscale three-dimensional shapes
- Cellular senescence: from physiology to pathology
- Mitochondrial cell death effectors.
- Persistent DNA damage signaling triggers senescence-associated inflammatory cytokine secretion
- Nanostructures: The manifold faces of DNA
- Senescent cells fail to express cdc2, cycA, and cycB in response to mitogen stimulation.
- Economic and social implications of aging societies
- Oxidation of the sugar moiety of DNA by ionizing radiation or bleomycin could induce the formation of a cluster DNA lesion
- The serial cultivation of human diploid cell strains.
- Folding and cutting DNA into reconfigurable topological nanostructures
- Rapid Chiral Assembly of Rigid DNA Building Blocks for Molecular Nanofabrication
- DNA-SCARS: distinct nuclear structures that sustain damage-induced senescence growth arrest and inflammatory cytokine secretion
- Hierarchical self-assembly of DNA into symmetric supramolecular polyhedra
- DNA prism structures constructed by folding of multiple rectangular arms.
- Clearance of p16Ink4a-positive senescent cells delays ageing-associated disorders
- DNA Origami with Complex Curvatures in Three-Dimensional Space
- Cataloging altered gene expression in young and senescent cells using enhanced differential display.
Cited by
- Tetrahedral Framework Nucleic Acids Promote Corneal Epithelial Wound Healing in Vitro and in Vivo.
- PEGylated protamine-based adsorbing improves the biological properties and stability of tetrahedral framework nucleic acids.
- Potent anti‐angiogenesis and anti‐tumour activity of pegaptanib‐loaded tetrahedral DNA nanostructure
- Neuroprotective and Neurotherapeutic Effects of Tetrahedral Framework Nucleic Acids on Parkinson's Disease in vitro.
- MicroRNA‐214‐3p modified tetrahedral framework nucleic acids target survivin to induce tumour cell apoptosis
- Pegylated carbon nitride nanosheets for enhanced reactive oxygen species generation and photodynamic therapy under hypoxic conditions.
- Study of PLGA microspheres loaded with pOsx/PEI nanoparticles for repairing bone defects in vivo and in vitro.
- Liposomal delivery of antibiotic loaded nucleic acid nanogels with enhanced drug loading and synergistic anti-inflammatory activity against S. aureus intracellular infections.
- Nucleic acid based tetrahedral framework DNA nanostructures for fibrotic diseases therapy
- Preventive effect of tetrahedral framework nucleic acids on bisphosphonate-related osteonecrosis of the jaw.
- Effects of the tetrahedral framework nucleic acids on the skeletal muscle regeneration in vitro and in vivo
- Tetrahedral framework nucleic acids promote scarless healing of cutaneous wounds via the AKT-signaling pathway
- Tetrahedral Framework Nucleic Acids Loading Ampicillin Improve the Drug Susceptibility against Methicillin-Resistant Staphylococcus aureus.
- Biomimetic phosphorylcholine-modified bacterial cellulose membranes with cell fouling resistance
- Progress in Biomedical Applications of Tetrahedral Framework Nucleic Acid-Based Functional Systems.
- The protective effect of tetrahedral framework nucleic acids on periodontium under inflammatory conditions
- The applications of functionalized DNA nanostructures in bioimaging and cancer therapy.
- Erythromycin loaded by tetrahedral framework nucleic acids are more antimicrobial sensitive against Escherichia coli (E. coli)
- Enhanced Penetrability of a Tetrahedral Framework Nucleic Acid by Modification with iRGD for DOX-Targeted Delivery to Triple-Negative Breast Cancer.
- The immune regulatory effects of tetrahedral framework nucleic acid on human T cells via the mitogen‐activated protein kinase pathway
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