Mechanism and medical implications of mammalian autophagy
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Summary
It is now apparent that autophagy is deregulated in the context of various human pathologies, including cancer and neurodegeneration, and its modulation has considerable potential as a therapeutic approach.
- Type
- review
- Published
- 2018-04-04
- Cited by
- 2,531
- References
- 199
- OpenAlex
- https://openalex.org/W2795845448
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:4594197
Keywords
Autophagy, Neurodegeneration, Cell biology, Context (archaeology), Biology
References
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- Autophagy as a promoter of longevity: insights from model organisms
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- Identification of a splice variant of optineurin which is defective in autophagy and phosphorylation.
- Fluid Shear Stress Promotes Autophagy in Hepatocellular Carcinoma Cells
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- Human ubiquitin-like proteins as central coordinators in autophagy
- Operation of mitochondrial machinery in viral infection-induced immune responses
- Palmitic acid induces human osteoblast-like Saos-2 cell apoptosis via endoplasmic reticulum stress and autophagy
- Autophagy: A new concept in autoimmunity regulation and a novel therapeutic option.
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- Autophagy in Adipose Tissue Physiology and Pathophysiology
- Hypoxia and Selective Autophagy in Cancer Development and Therapy
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