Wnt/β-catenin signaling and disease.

Keywords

Biology, Wnt signaling pathway, Disease, Catenin, Beta-catenin

References

• Negative Feedback Loop of Wnt Signaling through Upregulation of Conductin/Axin2 in Colorectal and Liver TumorsN.D. Brown, R.A. Passman — 2002
• Retinal vasculature changes in Norrie disease mice.Maik Richter, Johannes Gottanka, Christian Albrecht May — 1998
• Mutations in LRP5 or FZD4 underlie the common familial exudative vitreoretinopathy locus on chromosome 11q.Carmel Toomes, H.M. Bottomley, Richard M. Jackson — 2004
• The Metabolic and Molecular Bases of Inherited DiseaseR Charles Scriver — 2001
• arrow encodes an LDL-receptor-related protein essential for Wingless signallingMarcel Wehrli, Scott T. Dougan, Kim A. Caldwell — 2000
• The Xenopus Wnt effector XTcf-3 interacts with Groucho-related transcriptional repressorsJeroen P. Roose, Miranda Molenaar, Josi Peterson — 1998
• Genomic sequencing of colorectal adenocarcinomas identifies a recurrent VTI1A-TCF7L2 fusionAdam J. Bass, Michael S. Lawrence, Lear E. Brace — 2011
• Dickkopf-1 is a member of a new family of secreted proteins and functions in head inductionAndrei Glinka, Wei Wu, Hajo Delius — 1998
• An LDL-receptor-related protein mediates Wnt signalling in miceKathleen I. Pinson, Jane Brennan, Susan J. Monkley — 2000
• LDL-receptor-related proteins in Wnt signal transductionKeiko Tamai, Mikhail A. Semenov, Yoichi Kato — 2000
• Distinct β-catenins mediate adhesion and signalling functions in C. elegansHendrik C. Korswagen, Michael A. Herman, Hans Clevers — 2000
• Wnt signalling: What The X@# is WTX?Yannik Régimbald‐Dumas, Xi He — 2011
• Insights into Wnt binding and signalling from the structures of two Frizzled cysteine-rich domainsCharles E. Dann, Jen-Chih Hsieh, Amir Rattner — 2001
• Update on Wnt signaling in bone cell biology and bone diseaseDavid G. Monroe, Meghan E. McGee‐Lawrence, Merry Jo Oursler — 2011
• The segment polarity gene porcupine encodes a putative multitransmembrane protein involved in Wingless processing.Tatsuhiko Kadowaki, Elizabeth L. Wilder, John Klingensmith — 1996
• Variant of transcription factor 7-like 2 (TCF7L2) gene confers risk of type 2 diabetesStruan F.A. Grant, Guðmar Þorleifsson, Inga Reynisdóttir — 2006
• Single Lgr5 stem cells build crypt–villus structures in vitro without a mesenchymal nicheToshiro Sato, Robert G.J. Vries, Hugo J.G. Snippert — 2009
• Evidence that fold-change, and not absolute level, of β-catenin dictates Wnt signalingLea Goentoro, Marc W. Kirschner — 2009
• Activation of β-Catenin-Tcf Signaling in Colon Cancer by Mutations in β-Catenin or APCPatrice J. Morin, Andrew B. Sparks, Vladimír Kořínek — 1997
• Association of the APC tumor suppressor protein with catenins.Li-Kuo Su, Bert Vogelstein, Kenneth W. Kinzler — 1993

Cited by

• PAPTi: A Peptide Aptamer Interference Toolkit for Perturbation of Protein-Protein Interaction NetworksZbigniew Tarapata — 2013
• Wnt Secretion and Gradient FormationTeresa Bürge — 2013
• The Wnt signalling pathway is upregulated in an in vitro model of acquired tamoxifen resistant breast cancer義彦 山本 — 2013
• The transcription factor FOXM1 (Forkhead box M1): proliferation-specific expression, transcription factor function, target genes, mouse models, and normal biological roles.Ying‐Nan Chiu — 2013
• Secreted Wnt Antagonists During Eradication of Cytomegalovirus Infection in Solid Organ Transplant RecipientsJosé María Latorre — 2014
• Snail1-dependent control of embryonic stem cell pluripotency and lineage commitmentMaría Aparecida Bergamaschi — 2014
• Multi-targeted therapy of cancer by niclosamide: a new application for an old drugKen‐ichi Hirano, B.J. Smith, Nancy H. Colburn — 2014
• Stroma provides an intestinal stem cell niche in the absence of epithelial WntsZahra Kabiri, Gediminas Greicius, Babita Madan — 2014
• Chromomycins A2 and A3 from Marine Actinomycetes with TRAIL Resistance-Overcoming and Wnt Signal Inhibitory ActivitiesJim R. Paulsen and Reza Sarhangi — 2014
• Both Canonical and Non-Canonical Wnt Signaling Independently Promote Stem Cell Growth in Mammospheres千衣子 赤石 — 2014
• Influence of secreted frizzled receptor protein 1 (SFRP1) on neoadjuvant chemotherapy in triple negative breast cancer does not rely on WNT signalingCHRISTIAN GOMES SEIDL — 2014
• Wnt/β-catenin signaling induces the transcription of cystathionine-γ-lyase, a stimulator of tumor in colon cancer.Mohammad Hatta — 2014
• β-Catenin Signaling Drives Differentiation and Proinflammatory Function of IRF8-Dependent Dendritic CellsK. Togashi — 2015
• Prostate cancer cells induce osteoblastic differentiation via semaphorin 3A幸士 生田 — 2015
• The Mediator complex of Caenorhabditis elegans: insights into the developmental and physiological roles of a conserved transcriptional coregulatorMaría Belén Rey Légidos, Jesús Prado Mascuñano — 2015
• Canonical Wnt signaling in dendritic cells regulates Th1/Th17 responses and suppresses autoimmune neuroinflammation和成 池田, 幸雄 浜, 利幸 吉野 — 2015
• Removal of SOST or blocking its product sclerostin rescues defects in the periodontitis mouse modelChristine Shimizu — 2015
• New insights into the conserved mechanism of pluripotency maintenance.Francisco Javier Martínez Yubero — 2015
• Registered report: Wnt activity defines colon cancer stem cells and is regulated by the microenvironment健 中家 — 2015
• Canonical and noncanonical Wnt signaling in neural stem/progenitor cellsMarc Quincampoix — 2015

Related papers

• Wnt Isoform-Specific Interactions with Coreceptor Specify Inhibition or Potentiation of Signaling by LRP6 AntibodiesYan Gong, Eric Bourhis, Cecilia Chiu — 2010
• Head inducer Dickkopf-1 is a ligand for Wnt coreceptor LRP6.MIKHAIL V. SEMËNOV, Keiko Tamai, Barbara K. Brott — 2001
• Wnt-4 activates the canonical beta-catenin-mediated Wnt pathway and binds Frizzled-6 CRD: functional implications of Wnt/beta-catenin activity in kidney epithelial cells.Jon P. Lyons, Ulrich Mueller, Hong Ji — 2004
• β-Catenin-Independent Roles of Wnt/LRP6 Signaling.Sergio P. Acebrón, Christof Niehrs — 2016
• Wnt-5a inhibits the canonical Wnt pathway by promoting GSK-3–independent β-catenin degradationLilia Topol, Xueyuan Jiang, Hosoon Choi — 2003
• Phosphorylation-Dependent Regulation of WNT/Beta-Catenin SignalingKinjal Shah, Julhash U. Kazi — 2022
• Role of Osteoblasts in Wnt / β-catenin PathwayRen Xian — 2014