Multi-targeted therapy of cancer by niclosamide: a new application for an old drug

Keywords

Molecular biology, Gene product, Cytoplasm, Cell culture, Immunoprecipitation

References

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• Niclosamide: comprehensive profile.Badraddin M.H. Al‐Hadiya — 2005
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• Targeting cancer stem cells by inhibiting Wnt, Notch, and Hedgehog pathwaysNaoko Takebe, Pamela Jo Harris, Ronald Q. Warren — 2011
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Cited by

• “Do We Know Jack” About JAK? A Closer Look at JAK/STAT Signaling PathwayGonzalo San Segundo — 2018
• A role for deferasirox as an anti-neoplastic and chemosensitising agent in gastrointestinal cancerMatthew Bedford — 2015
• The Anthelmintic Drug Niclosamide Inhibits the Proliferative Activity of Human Osteosarcoma Cells by Targeting Multiple Signal Pathways.Zhan Liao, Guoxin Nan, Zhengjian Yan — 2015
• Significantly enhanced bioavailability of niclosamide through submicron lipid emulsions with or without PEG-lipid: a comparative studyXingwang Zhang, Yong Zhang, Tianpeng Zhang — 2015
• Metabolism of the anthelmintic drug niclosamide by cytochrome P450 enzymes and UDP-glucuronosyltransferases: metabolite elucidation and main contributions from CYP1A2 and UGT1A1Danyi Lu, Zhiguo Ma, Tianpeng Zhang — 2016
• Niclosamide Analogs for Treatment of Ovarian CancerChristen L. Walters Haygood, Rebecca C. Arend, Abhishek Gangrade — 2015
• Structure–activity studies of Wnt/β-catenin inhibition in the Niclosamide chemotype: Identification of derivatives with improved drug exposureRobert A. Mook, Jiangbo Wang, Xiu-Rong Ren — 2015
• Crohn's disease-derived monocytes fail to induce Paneth cell defensinsLioba Courth, Maureen J. Ostaff, Daniela Mailänder‐Sánchez — 2015
• Altered Gene Expression in the Schistosome-Transmitting Snail Biomphalaria glabrata following Exposure to Niclosamide, the Active Ingredient in the Widely Used Molluscicide BayluscideSi‐Ming Zhang, Sarah K. Buddenborg, Coen M. Adema — 2015
• Existing drugs and their application in drug discovery targeting cancer stem cellsJunfang Lv, Joong Sup Shim — 2015
• Niclosamide suppresses migration of hepatocellular carcinoma cells and downregulates matrix metalloproteinase-9 expression.M. Tomizawa, Fuminobu Shinozaki, Yasufumi Motoyoshi — 2015
• NFFinder: an online bioinformatics tool for searching similar transcriptomics experiments in the context of drug repositioningJavier Setoaín, Mónica Franch, Marta Martínez — 2015
• On the photooxidation of the multifunctional drug niclosamide. A kinetic study in the presence of vitamin B2 and visible lightJosé Natera, Eduardo Gatica, Cecilia Challier — 2015
• Enriched inhibition of cancer and stem-like cancer cells via STAT-3 modulating niclocelles.Santosh K. Misra, Tor Jensen, Dipanjan Pan — 2015
• Nifuroxazide induces apoptosis and impairs pulmonary metastasis in breast cancer modelFangfang Yang, Menglong Hu, Qianqian Lei — 2015
• Electrocatalytic activity of activated niclosamide on multi-walled carbon nanotubes glassy carbon electrode toward NADH oxidationCleylton Bezerra Lopes, Francisco de Assis dos Santos Silva, Phabyanno Rodrigues Lima — 2015
• Niclosamide inhibits the proliferation of human osteosarcoma cell lines by inducing apoptosis and cell cycle arrest.Zonghuan Li, Yifeng Yu, Shaoxing Sun — 2015
• Targeting the Wnt pathways for therapiesArtem Blagodatski, Dmitry Poteryaev, Vladimir L. Katanaev — 2014
• Design and evaluation of injectable niclosamide nanocrystals prepared by wet media milling techniqueYanghuan Ye, Xingwang Zhang, Tianpeng Zhang — 2015
• Niclosamide inhibits epithelial-mesenchymal transition and tumor growth in lapatinib-resistant human epidermal growth factor receptor 2-positive breast cancer.Junjun Liu, Xiaosong Chen, Toby M. Ward — 2016

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