The transcription factor FOXM1 (Forkhead box M1): proliferation-specific expression, transcription factor function, target genes, mouse models, and normal biological roles.
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Summary
The functions of FOXM1 in prevention of polyploidsy and aneuploidy and in homologous recombination repair of DNA-double-strand breaks suggest an importance of FOXm1 for the maintenance of genomic stability and chromosomal integrity.
- Type
- article
- Published
- 2013-01-01
- Cited by
- 178
- References
- 1,167
- OpenAlex
- https://openalex.org/W23768511
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:92323951
Keywords
Foundation (evidence), Mathematics, Law, Political science
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- Foxm1 is essential for quiescence and maintenance of hematopoietic stem cells
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