COX‐2 and cancer: a new approach to an old problem
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Summary
A large number of the patients treated with this drug had no history of adverse events and the use of this drug did not appear to have an adverse effect on their mental health.
- Type
- review
- Published
- 2001-11-01
- Cited by
- 131
- References
- 159
- Access
- Open access
- OpenAlex
- https://openalex.org/W1984422911
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:24122145
Keywords
Cancer, Medicine, Internal medicine
References
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- Combinatorial chemoprevention of intestinal neoplasia
- TIS10, a phorbol ester tumor promoter-inducible mRNA from Swiss 3T3 cells, encodes a novel prostaglandin synthase/cyclooxygenase homologue.
- Expression of HLA class I antigens in sporadic adenomas and histologically normal mucosa of the colon.
- Segregated coupling of phospholipases A2, cyclooxygenases, and terminal prostanoid synthases in different phases of prostanoid biosynthesis in rat peritoneal macrophages.
- Potential involvement of IL-10 in suppressing tumor-associated macrophages. Colon-26-derived prostaglandin E2 inhibits TNF-alpha release via a mechanism involving IL-10.
- Celecoxib inhibits N-butyl-N-(4-hydroxybutyl)-nitrosamine-induced urinary bladder cancers in male B6D2F1 mice and female Fischer-344 rats.
- Cyclooxygenase-2 in Barrett's Esophagus, Barrett's Adenocarcinomas, and Esophageal SCC: Ready for Clinical Trials
- Colorectal cancer risk, chronic illnesses, operations, and medications: case control results from the Melbourne Colorectal Cancer Study.
- Three secretory phospholipase A(2) genes that map to human chromosome 1P35-36 are not mutated in individuals with attenuated adenomatous polyposis coli.
- Inhibition of angiogenesis by nonsteroidal anti-inflammatory drugs: Insight into mechanisms and implications for cancer growth and ulcer healing
- Roles of PPARs in health and disease
- Up-regulation of cyclooxygenase 2 gene expression in human colorectal adenomas and adenocarcinomas.
- Modulation of apoptosis and Bcl-2 expression by prostaglandin E2 in human colon cancer cells.
- Nitric oxide synthase, cyclooxygenase 2, and vascular endothelial growth factor in the angiogenesis of non-small cell lung carcinoma.
- Inhibitors of prostaglandin synthesis inhibit human prostate tumor cell invasiveness and reduce the release of matrix metalloproteinases.
- Loss of colonic HLA antigens in familial adenomatous polyposis.
Cited by
- Enhancing radiotherapy with cyclooxygenase-2 enzyme inhibitors: a rational advance?
- Resveratrol as an anti-inflammatory and anti-aging agent: mechanisms and clinical implications.
- The Furoxan System: Design of Selective Nitric Oxide (NO) Donor Inhibitors of COX‐2 Endowed with Anti‐Aggregatory and Vasodilating Activities
- Polyphenols in Health and Disease
- IMUNOMARCAÇÃO DE COX 2, PGE-2, VEGF E CASPASE 3 EM MASTOCITOMAS CUTÂNEOS CANINOS
- INTERACCION DE DEXIBUPROFENO CON KETOPROFENO EN DOLOR AGUDO TERMICO EXPERIMENTAL
- PROLIFERAÇÃO CELULAR E EXPRESSÃO DA CICLOXIGENASE-2 COMO PARÂMETROS PROGNÓSTICOS NA CERATOSE ACTÍNICA E NO CARCINOMA DE CÉLULAS ESCAMOSAS CUTÂNEO EM CÃES
- -765G > C COX-2 polymorphism may be a susceptibility marker for gastric adenocarcinoma in patients with atrophy or intestinal metaplasia.
- Identification and functional activation of peroxisome proliferator-activated receptor in human upper aerodigestive cancer
- Cyclo-Oxygenase-2 and its Inhibition in Cancer
- COX-2 Inhibitors for Cancer Treatment in Dogs
- Changes chemopreventive markers in colorectal cancer development after inulin supplementation
- Inulin Diet Intervention on Chemopreventive and Inflammatory Markers in Tumorigenesis of Colorectal Cancer
- Cyclooxygenase-2 and prostate carcinogenesis.
- Activation of thromboxane receptor alpha induces expression of cyclooxygenase-2 through multiple signaling pathways in A549 human lung adenocarcinoma cells.
- Indomethacin induces apoptosis in 786-O renal cell carcinoma cells by activating mitogen-activated protein kinases and AKT.
- Dioscorea japonica extract down-regulates prostaglandin E2 synthetic pathway and induces apoptosis in lung cancer cells
- Lack of association of the cyclooxygenase-2 gene 8473T>C polymorphism with breast cancer risk: a meta-analysis.
- Evaluation of Expression of Apoptosis-Related Proteins and Their Correlation with HPV, Telomerase Activity, and Apoptotic Index in Cervical Cancer
- HER2 and COX2 expression in human prostate cancer.
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