Dioscorea japonica extract down-regulates prostaglandin E2 synthetic pathway and induces apoptosis in lung cancer cells
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Summary
The results suggest that Dioscorea japonica extract suppresses the expression of cyclooxygenase-2 and microsomal prostaglandin E synthase-1, with the regulation of the transcriptional activity of cycling, and induces apoptosis in cancer cells.
- Type
- article
- Published
- 2014-09-09
- Cited by
- 8
- References
- 34
- Access
- Open access
- OpenAlex
- https://openalex.org/W1975965114
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:582702
Keywords
Cyclooxygenase, Prostaglandin E2, Prostaglandin, Prostaglandin E2 receptor, Prostaglandin E
References
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- Effects of cooking on the nutrient and antinutrient contents of yam tubers (Dioscorea alata and Dioscorea esculenta)
- COX‐2 and cancer: a new approach to an old problem
- Isolation and hypoglycemic activity of dioscorans A, B, C, D, E, and F; glycans of Dioscorea japonica rhizophors.
- Resveratrol Inhibits Cyclooxygenase-2 Transcription and Activity in Phorbol Ester-treated Human Mammary Epithelial Cells*
- Induction of apoptosis by trichostatin A, a histone deacetylase inhibitor, is associated with inhibition of cyclooxygenase-2 activity in human non-small cell lung cancer cells.
- Isolation and identification of steroidal saponins in Taiwanese yam cultivar (Dioscorea pseudojaponica Yamamoto).
- Sulforaphane Inhibits Prostaglandin E2 Synthesis by Suppressing Microsomal Prostaglandin E Synthase 1
- Identification and characterization of a novel type of membrane-associated prostaglandin E synthase.
- Diosgenin targets Akt‐mediated prosurvival signaling in human breast cancer cells
- Cyclooxygenase-2 level and culture conditions influence NS398-induced apoptosis and caspase activation in lung cancer cells.
- Enhancement of antitumor activity of docetaxel by celecoxib in lung tumors
- A polymerase chain reaction-based method for constructing a linear vector with site-specific DNA methylation.
- Arachidonic Acid Cascade and Signal Transduction
- Suppression of cyclooxygenase‐2 gene transcription by humulon of beer hop extract studied with reference to glucocorticoid
Cited by
- Evaluation of anti-inflammatory activity and standardisation of hydro-methanol extract of underground tuber of Dioscorea alata
- Preventive effect of Dioscorea japonica on squamous cell carcinoma of mouse skin involving down-regulation of prostaglandin E2 synthetic pathway
- Changes in Results of Vital Signs, Blood Tests, and Functional Tests after Taking Cheongsimyeonja-tang
- Beneficial effect of additional treatment with widely available anticancer agents in advanced small lung cell carcinoma: A case report.
- Ellagitannins from Punica granatum leaves suppress microsomal prostaglandin E synthase-1 expression and induce lung cancer cells to undergo apoptosis
- Applicability of Swallowing Sounds and Electromyography for Assessing the Ease of Swallowing of Foods
- A Thickening Agent Using Dioscorea japonica Powder Exhibits Suitable Properties for People with Dysphagia
- The genus Dioscorea L. (Dioscoreaceae), a review of traditional uses, phytochemistry, pharmacology, and toxicity.
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