Loss of colonic HLA antigens in familial adenomatous polyposis.

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Summary

The generalized suppression of HLA gene expression in the colon of FAP patients, which precedes the onset of overt histological manifestations of neoplasia, may be an important early event in colon carcinogenesis.

Type
article
Published
1992-06-15
Cited by
27
References
0

Keywords

Familial adenomatous polyposis, Colorectal cancer, Antigen, Human leukocyte antigen, Immunohistochemistry

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