Loss of colonic HLA antigens in familial adenomatous polyposis.
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Summary
The generalized suppression of HLA gene expression in the colon of FAP patients, which precedes the onset of overt histological manifestations of neoplasia, may be an important early event in colon carcinogenesis.
- Type
- article
- Published
- 1992-06-15
- Cited by
- 27
- References
- 0
- OpenAlex
- https://openalex.org/W1812155523
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:475908
Keywords
Familial adenomatous polyposis, Colorectal cancer, Antigen, Human leukocyte antigen, Immunohistochemistry
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