Nitric oxide synthase, cyclooxygenase 2, and vascular endothelial growth factor in the angiogenesis of non-small cell lung carcinoma.
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Summary
The results indicate that angiogenesis is a complex process that involves multiple factors including NOS2, COX2, and VEGF and may explain the modest results observed in antiangiogenesis therapy that target a single protein.
- Type
- article
- Published
- 2000-12-01
- Cited by
- 210
- References
- 46
- OpenAlex
- https://openalex.org/W1787737644
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:1728536
Keywords
Angiogenesis, CD31, Lung cancer, Vascular endothelial growth factor, Pathology
References
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- Transforming growth factor β1 is associated with angiogenesis, metastasis, and poor clinical outcome in prostate cancer
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- The K-ras gene regulates vascular endothelial growth factor gene expression in non-small cell lung cancers.
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Cited by
- A risk model for non-small cell lung cancer using clinicopathological variables, angiogenesis and oncoprotein expression.
- Evaluation of microvascular density in tumors: pro and contra.
- Inducible nitric oxide synthase expression in human colorectal cancer: correlation with tumor angiogenesis.
- Role of nitric oxide in tumor angiogenesis.
- Clinicopathologic and prognostic significance of cyclooxygenase-2 expression in endometrial carcinoma.
- Cyclooxygenase-2 (cox-2) and the inflammogenesis of cancer.
- Relationship between inducible nitric oxide synthase expression and angiogenesis in primary gallbladder carcinoma tissue.
- Pathology and genetics of tumours of the lung , pleura, thymus and heart
- Genetic Predictors of Clinical Outcomes in Non-Small Cell Lung Cancer Patients
- Genetic ablation of inducible nitric oxide synthase decreases mouse lung tumorigenesis.
- Kliniczne znaczenie stopnia ekspresji cyklooksygenazy-2 (COX-2) w niedrobnokomórkowym raku płuca (NDRP)
- Cyclooxygenase-2 in lung cancer.
- Systems Pharmacology Dissecting Holistic Medicine for Treatment of Complex Diseases: An Example Using Cardiocerebrovascular Diseases Treated by TCM
- Cyclooxygenase‐2 promotes angiogenesis in pTa/T1 urothelial bladder carcinoma but does not predict recurrence
- Chemopreventive efficacy of green tea drinking against 1,2‐dimethyl hydrazine‐induced rat colon carcinogenesis
- Cyclooxygenase-2 gene and lung carcinoma risk
- Multifaceted roles of cyclooxygenase-2 in lung cancer.
- Expression of cyclooxygenase-2 in canine uveal melanocytic neoplasms.
- The Characteristics of Vascular Growth in VX2 Tumor Measured by MRI and Micro-CT
- Overexpression of Metastasis-Associated Protein 1 is Significantly Correlated with Tumor Angiogenesis and Poor Survival in Patients with Early-Stage Non-Small Cell Lung Cancer
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