A Review of Family-Based Tests for Linkage Disequilibrium between a Quantitative Trait and a Genetic Marker
Explore this paper's citation graph
Summary
This review aims at outlining the broad features of the various quantitative TDT procedures carried out in the frequently used QTDT and FBAT packages, as well as the various “Abecasis” and “Allison” regression-based procedures.
- Type
- review
- Published
- 2008-09-01
- Cited by
- 50
- References
- 12
- Access
- Open access
- OpenAlex
- https://openalex.org/W2093973621
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:17119940
Keywords
Biology, Linkage disequilibrium, Genetics, Quantitative trait locus, Disequilibrium
References
- Transmission test for linkage disequilibrium: the insulin gene region and insulin-dependent diabetes mellitus (IDDM).
- Implementing a unified approach to family‐based tests of association
- Removing the sampling restrictions from family-based tests of association for a quantitative-trait locus.
- A transmission disequilibrium test for quantitative trait loci.
- In silico method for inferring genotypes in pedigrees
- Power and design considerations for a general class of family-based association tests: quantitative traits.
- Transmission/disequilibrium tests for quantitative traits
- Tests for linkage and association in nuclear families.
- A general test of association for quantitative traits in nuclear families.
- A unified mixed-model method for association mapping that accounts for multiple levels of relatedness
- A new multipoint method for genome-wide association studies by imputation of genotypes
Cited by
- Etude des relations génotype/phénotype dans le rétinoblastome
- Design and Interpretation of Linkage and Association Studies on Osteoporosis
- Variance-Components Methods for Linkage and Association Analysis of Ordinal Traits in General Pedigrees
- Alpha-tryptase gene variation is associated with levels of circulating IgE and lung function in asthma
- Replication of CNTNAP2 association with nonword repetition and support for FOXP2 association with timed reading and motor activities in a dyslexia family sample
- Robust QTL fine mapping by applying a quantitative transmission disequilibrium test to the Mendelian sampling term.
- Twins for epigenetic studies of human aging and development
- Pedigree transmission disequilibrium test for quantitative traits in farm animals
- A statistical framework for testing the causal effects of fetal drive
- Dissecting complex phenotypes using the genomics of twins
- Fast dimension-reduced climate model calibration and the effect of data aggregation
- LEVERAGING LOCAL IDENTITY-BY-DESCENT INCREASES THE POWER OF CASE/CONTROL GWAS WITH RELATED INDIVIDUALS
- Family-based designs for genome-wide association studies
- A Review of Genetic Association Analyses in Population and Family Based Data: Methods and Software
- A Rapid Generalized Least Squares Model for a Genome-Wide Quantitative Trait Association Analysis in Families
- Population structure and association mapping of flower-related traits in lotus (Nelumbo Adans.) accessions
- Gene-environment interaction tests for family studies with quantitative phenotypes: A review and extension to longitudinal measures
- The causal meaning of Fisher’s average effect
- Twin-based DNA methylation analysis takes the center stage of studies of human complex diseases.
- Second-generation PLINK: rising to the challenge of larger and richer datasets
Related papers
- Disequilibrium Market Analysis: An Application to the U.S. Fed Beef Sector
- An Explanation of the Implication of Regional Coordination Based on the Theory of Disequilibrium Development
- Modeling winegrape prices in disequilibrium
- SOME METHODOLOGY PROBLEMS FOR DISEQUILIBRIUM MODELS
- Research on Regulation Control for Multi-Market Disequilibrium Model
- A primary study on disequilibrium transportation planning
- Decay of linkage disequilibrium in a finite island model.
- Modeling Extent and Distribution of Zygotic Disequilibrium: Implications for a Multigenerational Canine Pedigree
- Gametic disequilibrium and physical distance.