Implementing a unified approach to family‐based tests of association
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Summary
A broad class of family‐based association tests that are adjusted for admixture; use either dichotomous or measured phenotypes; accommodate phenotype‐unknown subjects; use nuclear families, sibships or a combination of the two, permit multiple nuclear families from a single pedigree; incorporate di‐ or multi‐allelic marker data; and permit adjustment for covariates and gene‐by‐environment interactions are described.
- Type
- article
- Published
- 2000-01-01
- Cited by
- 911
- References
- 15
- OpenAlex
- https://openalex.org/W1977945634
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:400747
Keywords
Test statistic, Covariate, Statistic, Trait, Statistics
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