Pedigree transmission disequilibrium test for quantitative traits in farm animals
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Summary
Compared with the existing pedigree disequilibrium test (PDT) and general linear model-based method QTDT, this approach performed better with higher power and lower type I error, especially in scenarios where the quantitative trait locus (QTL) effect was small.
- Type
- article
- Published
- 2012-07-12
- Cited by
- 1
- References
- 18
- Access
- Open access
- OpenAlex
- https://openalex.org/W2011885831
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:84679386
Keywords
Pedigree chart, Disequilibrium, Linkage disequilibrium, Transmission disequilibrium test, Genotyping
References
- Family-based designs in the age of large-scale gene-association studies
- Transmission test for linkage disequilibrium: the insulin gene region and insulin-dependent diabetes mellitus (IDDM).
- Comparing Linkage Disequilibrium-Based Methods for Fine Mapping Quantitative Trait Loci
- On a general class of conditional tests for family‐based association studies in genetics: the asymptotic distribution, the conditional power, and optimality considerations
- A discordant-sibship test for disequilibrium and linkage: no need for parental data.
- Selective genotyping for determination of linkage between a marker locus and a quantitative trait locus
- A transmission disequilibrium test for quantitative trait loci.
- Transmission/disequilibrium tests for quantitative traits
- Tests for linkage and association in nuclear families.
- A test for linkage and association in general pedigrees: the pedigree disequilibrium test.
- Pedigree tests of transmission disequilibrium
- Family-based tests of association and linkage that use unaffected sibs, covariates, and interactions.
- A Review of Family-Based Tests for Linkage Disequilibrium between a Quantitative Trait and a Genetic Marker
- A generalized family-based association test for dichotomous traits.
- Transmission/disequilibrium tests using multiple tightly linked markers.
- A sibship test for linkage in the presence of association: the sib transmission/disequilibrium test.
- Introduction to Quantitative Genetics.
- Introduction to Quantitative Genetics.
- Respiratory Genetics
- Letter to the Editor Correcting for a Potential Bias in the Pedigree Disequilibrium Test
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