Towards a systems understanding of MHC class I and MHC class II antigen presentation
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Summary
A timely evaluation of the biology of antigen presentation and a survey of issues that are considered unresolved are presented.
- Type
- review
- Published
- 2011-12-01
- Cited by
- 2,005
- References
- 158
- OpenAlex
- https://openalex.org/W2073621589
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:205491475
Keywords
Antigen processing, MHC class I, Antigen presentation, Major histocompatibility complex, Presentation (obstetrics)
References
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- Tapasin Is a Facilitator, Not an Editor, of Class I MHC Peptide Binding 1
- Major histocompatibility complex class I binding predictions as a tool in epitope discovery
- A caspase-independent pathway of MHC class II antigen-mediated apoptosis of human B lymphocytes.
- Combining radiation and immunotherapy for synergistic antitumor therapy
- Cutting Edge: MHC Class II Expression by Pulmonary Nonhematopoietic Cells Plays a Critical Role in Controlling Local Inflammatory Responses
- Antigen presentation by interferon-gamma-treated endothelial cells and fibroblasts: differential ability to function as antigen-presenting cells despite comparable Ia expression.
- Autophagy and adaptive immunity
- Rapid degradation of a large fraction of newly synthesized proteins by proteasomes
- Cutting Edge: HLA-B27 Acquires Many N-Terminal Dibasic Peptides: Coupling Cytosolic Peptide Stability to Antigen Presentation1
- Endoplasmic Reticulum Aminopeptidase Associated with Antigen Processing Defines the Composition and Structure of MHC Class I Peptide Repertoire in Normal and Virus-Infected Cells
- Upregulation of cathepsin S in psoriatic keratinocytes
Cited by
- Anti-microbial peptides in inflammatory bowel disease
- Direct evidence that the N-terminal extensions of the TAP complex act as autonomous interaction scaffolds for the assembly of the MHC I peptide-loading complex
- Major Histocompatibility Complex Class II+ Invariant Chain Negative Breast Cancer Cells Present Unique Peptides that Activate Tumor-specific T Cells from Breast Cancer Patients*
- In silico peptide-binding predictions of passerine MHC class I reveal similarities across distantly related species, suggesting convergence on the level of protein function
- CD8+ T-cell auto-reactivity is dependent on the expression of the immunoproteasome subunit LMP7 in exposed to lipopolysaccharide antigen presenting cells and epithelial target cells
- Studying MHC class II transport in dendritic cells.
- Different antigen processing activities in dendritic cells, macrophages and monocytes lead to uneven production of HIV epitopes and affect CTL recognition
- Myofiber HLA-DR expression is a distinctive biomarker for antisynthetase-associated myopathy
- Positive-selection-inducing self-peptides displayed by cortical thymic epithelial cells.
- [A new mechanism of autoantibody production: antigen presentation of misfolded protein by MHC class II].
- Association of Polymorphisms in HLA Antigen Presentation-Related Genes with the Outcomes of HCV Infection
- Hypoxia and inflammatory bowel disease.
- Platelet proteome reveals novel pathways of platelet activation and platelet-mediated immunoregulation in dengue
- Cis-Regulatory Evolution in a Wild Primate: Infection-Associated Genetic Variation Drives Differential Expression of MHC-DQA1 In-Vitro
- Therapeutic Effect of Exogenous Truncated IK Protein in Inflammatory Arthritis
- A Targeted LC‐MS Strategy for Low‐Abundant HLA Class‐I‐Presented Peptide Detection Identifies Novel Human Papillomavirus T‐Cell Epitopes
- Stem-cell based organ-on-a-chip models for diabetes research.
- Assaying peptide translocation by the peptide transporter TAP.
- Immunological benefits of a novel polycaprolactone-polyorthoester-based therapeutic vaccine in a mouse model of glioma
- The PINK1 repertoire: Not just a one trick pony
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