Monitoring Antigen Processing for MHC Presentation via Macroautophagy.
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Summary
This chapter describes three basic experiments for the monitoring and manipulation of macroautophagic antigen processing toward MHC class II presentation through the canonical pathway and describes how macroautrophagy can be silenced in antigen presenting cells, like human monocyte-derived dendritic cells (DCs).
- Type
- article
- Published
- 2019-01-01
- Cited by
- 2
- References
- 25
- Access
- Open access
- OpenAlex
- https://openalex.org/W2947275813
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:171092344
Keywords
Antigen processing, MHC class I, Antigen presentation, MHC class II, Cell biology
References
- Chaperone-mediated autophagy in aging and disease.
- Antigen Processing by Macroautophagy for MHC Presentation
- Atg8, a ubiquitin-like protein required for autophagosome formation, mediates membrane tethering and hemifusion.
- Autophagy enhances the efficacy of BCG vaccine by increasing peptide presentation in mouse dendritic cells
- Mammalian autophagy: core molecular machinery and signaling regulation
- In Vivo Requirement for Atg5 in Antigen Presentation by Dendritic Cells
- Nuclear location of an endogenously expressed antigen, EBNA1, restricts access to macroautophagy and the range of CD4 epitope display
- A role for ubiquitin in selective autophagy.
- Autophagy in immunity and inflammation
- Routes to manipulate MHC class II antigen presentation.
- Efficient Cross-presentation Depends on Autophagy in Tumor Cells
- Endogenous MHC Class II Processing of a Viral Nuclear Antigen After Autophagy
- Autophagy of pathogens alarms the immune system and participates in its effector functions.
- Antigen-loading compartments for major histocompatibility complex class II molecules continuously receive input from autophagosomes.
- Autophagy promotes MHC class II presentation of peptides from intracellular source proteins
- Autophagy within the antigen donor cell facilitates efficient antigen cross-priming of virus-specific CD8+ T cells
- Macroautophagy during Innate Immune Activation
- Enhancing immunity through autophagy.
- MICROAUTOPHAGY OF CYTOSOLIC PROTEINS BY LATE ENDOSOMES
- Alternative Endogenous Protein Processing via an Autophagy-Dependent Pathway Compensates for Yersinia-Mediated Inhibition of Endosomal Major Histocompatibility Complex Class II Antigen Presentation
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