Role of autophagy in MHC class I-restricted antigen presentation
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Summary
The role of autophagy, an intracellular degradation system that delivers cytoplasmic constituents to lysosomes, in MHC class I-restricted antigen presentation is discussed.
- Type
- review
- Published
- 2017-11-08
- Cited by
- 50
- References
- 38
- Access
- Open access
- OpenAlex
- https://openalex.org/W2767921026
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:13134902
Keywords
Antigen processing, MHC class I, Cross-presentation, Antigen presentation, Major histocompatibility complex
References
- Differential use of autophagy by primary dendritic cells specialized in cross-presentation
- Nuclear membrane-derived autophagy, a novel process that participates in the presentation of endogenous viral antigens during HSV-1 infection
- Autophagy mediates transporter associated with antigen processing-independent presentation of viral epitopes through MHC class I pathway.
- In Vivo Requirement for Atg5 in Antigen Presentation by Dendritic Cells
- The quality control of MHC class I peptide loading
- Modulation of antigen presentation by intracellular trafficking.
- Engulfment of apoptotic cells: signals for a good meal
- DRiPs Solidify: Progress in Understanding Endogenous MHC Class I Antigen Processing
- Efficient Cross-presentation Depends on Autophagy in Tumor Cells
- TIM-4 glycoprotein-mediated degradation of dying tumor cells by autophagy leads to reduced antigen presentation and increased immune tolerance.
- Vaccine Activation of the Nutrient Sensor GCN2 in Dendritic Cells Enhances Antigen Presentation
- Antigen-loading compartments for major histocompatibility complex class II molecules continuously receive input from autophagosomes.
- Autophagy within the antigen donor cell facilitates efficient antigen cross-priming of virus-specific CD8+ T cells
- Pathways of Antigen Processing
- Major histocompatibility complex class I-restricted antigen processing and presentation.
- Autophagy and the immune system.
- The role of Atg proteins in autophagosome formation.
- Alpha-alumina nanoparticles induce efficient autophagy-dependent cross-presentation and potent antitumour response
- Guidelines for the use and interpretation of assays for monitoring autophagy
- Amphisomal Route of MHC Class I Cross-Presentation in Bacteria-Infected Dendritic Cells
Cited by
- Autophagy: A new concept in autoimmunity regulation and a novel therapeutic option.
- Restriction Factors: From Intrinsic Viral Restriction to Shaping Cellular Immunity Against HIV-1
- Modulation of Autophagy for Controlling Immunity
- ERAP1 shapes just part of the immunopeptidome.
- Autophagy protein ATG5 regulates CD36 expression and anti-tumor MHC class II antigen presentation in dendritic cells
- Rainbow Trout Red Blood Cells Exposed to Viral Hemorrhagic Septicemia Virus Up-Regulate Antigen-Processing Mechanisms and MHC I&II, CD86, and CD83 Antigen-presenting Cell Markers
- Helicobacter pylori Deregulates T and B Cell Signaling to Trigger Immune Evasion
- Grass carp ATG5 and ATG12 promote autophagy but down-regulate the transcriptional expression levels of IFN-I signaling pathway.
- Interactions between Autophagy and DNA Viruses
- Major histocompatibility complex class I (MHC Iα) of Japanese flounder (Paralichthys olivaceus) plays a critical role in defense against intracellular pathogen infection.
- Autophagy and the Immune Response
- HIV-1 Nef counteracts autophagy restriction by enhancing the association between BECN1 and its inhibitor BCL2 in a PRKN-dependent manner
- Screening of immune biomarkers in different breeds of chickens infected with J subgroup of avian leukemia virus by proteomic
- Understanding the Pathogenesis of Spondyloarthritis
- Molecular cloning, characterization and expression analysis of major histocompatibility complex class I alpha gene of pufferfish (Takifugu obscurus).
- Emerging role of autophagy in anti-tumor immunity: Implications for the modulation of immunotherapy resistance.
- Autophagy in Viral Development and Progression of Cancer
- Modulation of Endosome Function, Vesicle Trafficking and Autophagy by Human Herpesviruses
- Dendritic cell PIK3C3/VPS34 controls the pathogenicity of CNS autoimmunity independently of LC3-associated phagocytosis
- Autophagy drives plasticity and functional polarization of tumor‐associated macrophages
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