Specific Patterns of Electrophile Adduction Trigger Keap1 Ubiquitination and Nrf2 Activation*

Keywords

KEAP1, Chemistry, Ubiquitin, Biochemistry, Transcription factor

References

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Cited by

• Discovery and characterization of inflammation-induced electrophilic fatty acid derivativesAlison L. Groeger — 2009
• Toward an "omic" physiopathology of reactive chemicals: thirty years of mass spectrometric study of the protein adducts with endogenous and xenobiotic compounds.Michael Jones — 2009
• The Nrf2-Antioxidant Response Element Signaling Pathway and Its Activation by Oxidative Stress*Ian Jones, D. Curtis Mumford — 2009
• Utilization of Dimethyl Fumarate and Related Molecules for Treatment of Multiple Sclerosis, Cancer, and Other DiseasesPatrick Mbataru — 2016
• Advances in Mechanisms of Anti-oxidationQiang Ma — 2014
• PGAM5, a Bcl-XL-interacting Protein, Is a Novel Substrate for the Redox-regulated Keap1-dependent Ubiquitin Ligase Complex*Shih‐Ching Lo, Mark Hannink — 2006
• Review of molecular mechanisms involved in the activation of the Nrf2-ARE signaling pathway by chemopreventive agents.Aldo Giudice, Claudio Arra, Maria Caterina Turco — 2010
• Induction of innate immune responses by plant-derived procyanidins and polysaccharidesJeff Holderness — 2012
• Analysis of protein adduction kinetics by quantitative mass spectrometry: competing adduction reactions of glutathione-S-transferase P1-1 with electrophiles.Christopher R. Orton, D.C. Liebler — 2007
• Mass spectrometry approaches for the redox characterization of protein cysteine residues the case of the transcription factor Pax-8.Andrea Scaloni, Gianluca Tell — 2010
• Régulation redox des facteurs des transcriptions de la famille CNC-bZip Nrf2 et Bach2S. Fourquet — 2008
• TRP channels as sensors of cellular redox statusN. Takahashi — 2010
• The Keap1-Nrf2 cell defense pathway--a promising therapeutic target?Ian M. Copple — 2012
• Mechanisms by which natural polyphenols regulate the expression of cytoprotective genesHan Xiao — 2010
• ANALYSIS OF ELECTROPHILE-INDUCED NRF2 GENE ACTIVATIONFei Hong — 2005
• ANALYSIS OF PROTEIN ADDUCTION KINETICS AND THE EFFECTS OF PROTEIN ADDUCTION ON C-JUN N-TERMINAL KINASE SIGNALINGChristopher R. Orton — 2006
• Early Responses to Oxidative Stress In Heart Cells: Signals From The Cell Membrane To The Nucleus and BeyondSally E. Purdom-Dickinson — 2005
• The complexity of the Nrf2 pathway: Beyond the antioxidant responseYing Huang, Wenji Li, Zheng‐Yuan Su — 2015
• An Untargeted Proteomics and Systems-based Mechanistic Investigation of Artesunate in Human Bronchial Epithelial CellsKodihalli C. Ravindra, Wanxing Eugene Ho, Cheng Chang — 2015
• Design, Synthesis, and Evaluation of Triazole Derivatives That Induce Nrf2 Dependent Gene Products and Inhibit the Keap1-Nrf2 Protein-Protein Interaction.Hélène Bertrand, Marjolein Schaap, Liam Baird — 2015

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