AH/PH domain-mediated interaction between Akt molecules and its potential role in Akt regulation

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Summary

Evidence is presented that the AH/PH domain is a domain of protein-protein interaction which mediates the formation of Akt protein complexes and the interaction between c-akt AH/ PH domains is highly specific, as determined by the failure of this domain to bind AKT2.

Type
article
Published
1995-04-01
Cited by
178
References
30
Access
Open access

Keywords

Biology, Protein kinase B, Proto-Oncogene Proteins c-akt, Domain (mathematical analysis), Cell biology

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