Why do we age?
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Summary
The evolutionary theory of ageing explains why ageing occurs and helps to clarify how the genome shapes the ageing process, thereby aiding the study of the genetic factors that influence longevity and age-associated diseases.
- Type
- review
- Published
- 2000-11-09
- Cited by
- 1,788
- References
- 76
- OpenAlex
- https://openalex.org/W1658682427
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:2579770
Keywords
Ageing, Longevity, Evolutionary biology, Biology, Senescence
References
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- Another set of responses and correlated responses to selection on age at reproduction in Drosophila melanogaster
- Life extension by dietary restriction in the bowl and doily spider, Frontinella pyramitela.
- The origin and evolution of menopause: The altriciality-lifespan hypothesis
- A test of evolutionary theories of senescence
- Effects of experimentally altered life spans on the accumulation of flourescent age pigment in the housefly, Musca domestica.
- Evolution of ageing
Cited by
- New science for an old problem.
- Decrease in the relative heterogeneity of health with age: a cross-national comparison.
- Spend less, live longer. The "thrifty aged" hypothesis.
- The extreme arrogance of anti-aging medicine
- Rapamycin: the cure for all that ails.
- Phenotypic plasticity and longevity in plants and animals: cause and effect?
- Parental Age and Lifespan Influence Offspring Recruitment: A Long-Term Study in a Seabird
- Nucleotide diversity inflation as a genome-wide response to experimental lifespan extension in Drosophila melanogaster
- The Evolutionary Consequences of Stepwise Infection Processes.
- Daughters of the budding yeast from old mothers have shorter replicative lifespans but not total lifespans. Are DNA damage and rDNA instability the factors that determine longevity?
- Understanding the roles of Non-homologous end joining and p53 after DNA damage
- The acquired immune system: a vantage from beneath.
- On aging and the role of Ubp3 in heterochromatic gene silencing and protein quality control
- An Analysis of Estrogen Metabolism and Breast Cancer Risk
- Telomere length in cardiovascular disease and type 2 diabetes
- The Cambridge handbook of age and ageing
- Links between Aging and Proteostasis Decline in Saccharomyces cerevisiae
- A regulated response to mitochondrial dysfunction modulates longevity and rates of living
- HEAD-TO-HEAD DEBATE: IS THERE A PROGRAM FOR AGING? Is aging programed?
- Menopause in type 1 diabetic women: is it premature?
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