Daughters of the budding yeast from old mothers have shorter replicative lifespans but not total lifespans. Are DNA damage and rDNA instability the factors that determine longevity?
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Summary
It is shown for the first time that daughter cells of an old mother have a reset lifespan expressed in units of time despite drastic reduction of their budding lifespan, which suggests that a single yeast cell has a fixed programmed longevity regardless of the time point at which it was originated.
- Type
- article
- Published
- 2018-05-19
- Cited by
- 9
- References
- 82
- Access
- Open access
- OpenAlex
- https://openalex.org/W2808291131
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:48357850
Keywords
Biology, Longevity, Budding yeast, Budding, Genome instability
References
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Cited by
- Dual roles of mitochondrial fusion gene FZO1 in yeast age asymmetry and in longevity mediated by a novel ATG32-dependent retrograde response
- Impact of curcumin on replicative and chronological aging in the Saccharomyces cerevisiae yeast
- Genome-wide screens in yeast models towards understanding chronological lifespan regulation
- Genetic interaction between glyoxylate pathway regulator UCC1 and La‐motif‐encoding SRO9 regulates stress response and growth rate improvement in Saccharomyces cerevisiae
- Evaluation of In Situ Antiaging Activity in Saccharomyces cerevisiae BY611 Yeast Cells Treated with Polyalthia longifolia Leaf Methanolic Extract (PLME) Using Different Microscopic Approaches: A Morphology-Based Evaluation
- Depletion of the Origin Recognition Complex Subunits Delays Aging in Budding Yeast
- Increasing the number of ribosomal uL6 mRNA copies accelerates aging of the budding yeast
- Threshold inclusion size triggers conversion of huntingtin to prion-like state that is reversible in newly born cells
- Caloric restriction enhances inheritance of wild-type mitochondrial DNA in Saccharomyces cerevisiae
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