Nuclear Localization of the Mitochondrial Factor HIGD1A during Metabolic Stress
Explore this paper's citation graph
Summary
A novel nuclear localization of HIGD1A is demonstrated that is commonly observed in human disease processes in vivo, frequently observed in diverse pathological states such as myocardial infarction, hypoxic-ischemic encephalopathy (HIE), and different types of cancer.
- Type
- article
- Published
- 2013-04-30
- Cited by
- 37
- References
- 73
- Access
- Open access
- OpenAlex
- https://openalex.org/W23646141
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:16370623
Keywords
Humanities, Art, Philosophy
References
- Glyceraldehyde-3-phosphate dehydrogenase: nuclear translocation participates in neuronal and nonneuronal cell death.
- Selective silencing of the hypoxia-inducible factor 1 target gene BNIP3 by histone deacetylation and methylation in colorectal cancer
- Cell Biology of Ischemia/Reperfusion Injury
- The involvement of hypoxia-inducible transcription factor-1-dependent pathway in nickel carcinogenesis.
- Bcl-2 proteins: regulators of apoptosis or of mitochondrial homeostasis?
- cDNA Microarray Analysis of Changes in Gene Expression Induced by Neuronal Hypoxia in Vitro
- Mitochondrio‐nuclear translocation of AIF in apoptosis and necrosis
- Apoptosis-Inducing Factor: Structure, Function, and Redox Regulation
- O2 regulates stem cells through Wnt/β-catenin signalling
- Circulating tumour cells demonstrate an altered response to hypoxia and an aggressive phenotype
- Abnormal angiogenesis and responses to glucose and oxygen deprivation in mice lacking the protein ARNT
- The survival effect of mitochondrial Higd-1a is associated with suppression of cytochrome C release and prevention of caspase activation.
- Oxygen sensing by metazoans: the central role of the HIF hydroxylase pathway.
- How do Bax and Bak lead to permeabilization of the outer mitochondrial membrane?
- Hypoxia Inducible Carbonic Anhydrase IX, Marker of Tumour: Hypoxia, Survival Pathway and Therapy Target
- ROLE OF BNIP3 AND NIX IN CELL DEATH, AUTOPHAGY, AND MITOPHAGY
- Pancreatic beta cells lack a low glucose and O2-inducible mitochondrial protein that augments cell survival.
- ECM-Dependent HIF Induction Directs Trophoblast Stem Cell Fate via LIMK1-Mediated Cytoskeletal Rearrangement
- Cytochrome c: functions beyond respiration
- C. elegans EGL-9 and mammalian homologs define a family of dioxygenases that regulate HIF by prolyl hydroxylation.
Cited by
- HIGD1A-mediated dormancy and tumor survival
- Aglycemia keeps mitochondrial oxidative phosphorylation under hypoxic conditions in HepG2 cells
- HIGD1A regulates oxygen consumption, ROS production and AMPK activity during glucose deprivation to modulate cell survival and tumor growth
- Depletion of suppressor of cytokine signaling-1a causes hepatic steatosis and insulin resistance in zebrafish.
- Differential Protein Distribution between the Nucleus and Mitochondria: Implications in Aging
- Role of oxidative stress and antioxidants in daily nutrition and human health.
- Mutational Analysis of the QRRQ Motif in the Yeast Hig1 Type 2 Protein Rcf1 Reveals a Regulatory Role for the Cytochrome c Oxidase Complex*
- Phosphorylation of cytochrome C: functional and structural features
- Integrated analyses of multi-omics reveal global patterns of methylation and hydroxymethylation and screen the tumor suppressive roles of HADHB in colorectal cancer
- The Expression of Hypoxia-Induced Gene 1 (Higd1a) in the Central Nervous System of Male and Female Rats Differs According to Age
- Screening of key candidate genes and pathways for osteocytes involved in the differential response to different types of mechanical stimulation using a bioinformatics analysis
- The yeast mitochondrial proteins Rcf1 and Rcf2 support the enzymology of the cytochrome c oxidase complex and generation of the proton motive force
- Targeted OMA1 therapies for cancer
- The OXPHOS supercomplex assembly factor HIG2A responds to changes in energetic metabolism and cell cycle
- Higd1a Protects Cells from Lipotoxicity under High-Fat Exposure
- CHUK/IKK-α loss in lung epithelial cells enhances NSCLC growth associated with HIF up-regulation
- Rcf1 Modulates Cytochrome c Oxidase Activity Especially Under Energy-Demanding Conditions
- Quantitative proteomics analysis of young and elderly skin with DIA mass spectrometry reveals new skin aging-related proteins
- HIGD-Driven Regulation of Cytochrome c Oxidase Biogenesis and Function
- Computational Approaches for Cancer-Fighting: From Gene Expression to Functional Foods
Related papers
No related papers recorded.