Cell Biology of Ischemia/Reperfusion Injury
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Summary
It is apparent that a combination of molecular and cellular approaches targeting multiple pathologic processes to limit the extent of I/R injury must be adopted to enhance resistance to cell death and increase regenerative capacity in order to effect long-lasting repair of ischemic tissues.
- Type
- review
- Published
- 2012-01-01
- Cited by
- 2,000
- References
- 511
- Access
- Open access
- OpenAlex
- https://openalex.org/W204998232
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:2317502
Keywords
Ischemia, Biology, Mitochondrial permeability transition pore, Programmed cell death, Intracellular
References
- Mast cells and leukotrienes mediate neutrophil sequestration and lung edema after remote ischemia in rodents.
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- Association of NKT cells and granulocytes with liver injury after reperfusion of the portal vein.
- Ceramide mediates caspase‐independent programmed cell death
- Platelet dynamics in the early phase of postischemic liver in vivo.
- An emerging role of mast cells in cerebral ischemia and hemorrhage
- p66SHC-mediated mitochondrial dysfunction in renal proximal tubule cells during oxidative injury.
- Calpain translocation and activation as pharmacological targets during myocardial ischemia/reperfusion.
- Influence of genetic background on ex vivo and in vivo cardiac function in several commonly used inbred mouse strains.
- Mitochondria and heart failure: new insights into an energetic problem
- Mildronate, a Novel Fatty Acid Oxidation Inhibitor and Antianginal Agent, Reduces Myocardial Infarct Size Without Affecting Hemodynamics
- Influence of SB203580 on cell apoptosis and P38MAPK in renal ischemia/reperfusion injury
- The mitochondrial permeability transition pore.
- Oxidized low-density lipoproteins and microvascular responses to ischemia-reperfusion.
- Free radical-mediated reperfusion injury: a selective review.
- Association of outcome with early stroke treatment: pooled analysis of ATLANTIS, ECASS, and NINDS rt-PA stroke trials.
- Myocardial Reperfusion Injury
- Cytochrome p450 2C (CYP2C) in ischemic heart injury and vascular dysfunction.
Cited by
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- Mechanisms and consequences of injury and repair in older organ transplants
- A new formula as a predictive score of post-liver transplantation outcome: postoperative MELD-lactate.
- Reduction of Mitochondria–Endoplasmic Reticulum Interactions by Acetylcholine Protects Human Umbilical Vein Endothelial Cells From Hypoxia/Reoxygenation Injury
- Controlled reperfusion reduces hemorheological alterations in a porcine infrarenal aortic-clamping ischemia-reperfusion model
- ERK phosphorylation plays an important role in the protection afforded by hypothermia against renal ischemia‐reperfusion injury
- Remote ischemic preconditioning attenuates EGR-1 expression following myocardial ischemia reperfusion injury through activation of the JAK-STAT pathway.
- Protective effect of ischemic preconditioning on testis injury following transient focal cerebral ischemia in diabetic rats
- Acute and long-term cardioprotective effects of the Traditional Chinese Medicine MLC901 against myocardial ischemia-reperfusion injury in mice
- Combined Treatment With Dichloroacetic Acid and Pyruvate Reduces Hippocampal Neuronal Death After Transient Cerebral Ischemia
- Remote Ischemic Preconditioning Does Not Affect the Release of Humoral Factors in Propofol-Anesthetized Cardiac Surgery Patients: A Secondary Analysis of the RIPHeart Study
- A Prospective Randomized Clinical Trial of a Novel, Noninvasive Perfusion Enhancement System for the Prevention of Hospital-Acquired Sacral Pressure Injuries
- Chick Embryo: A Preclinical Model for Understanding Ischemia-Reperfusion Mechanism
- Inhibition of Postinfarction Ventricular Remodeling by High Molecular Weight Polyethylene Glycol.
- N6-methyladenosine reader YTH N6-methyladenosine RNA binding protein 3 or insulin like growth factor 2 mRNA binding protein 2 knockdown protects human bronchial epithelial cells from hypoxia/reoxygenation injury by inactivating p38 MAPK, AKT, ERK1/2, and NF-κB pathways
- Role of mineralocorticoid receptor regulation during experimental myocardial infarction
- Ischemia-reperfusion injury in sickle cell anemia: relationship to acute chest syndrome, endothelial dysfunction, arterial vasculopathy, and inflammatory pain.
- Die Rolle der Ekto-5´-Nukleotidase (CD73) bei der Entzündungsreaktion nach Herzinfarkt in der Maus
- Oxygen-glucose deprivation and reoxygenation as an in vitro ischemia-reperfusion injury model for studying blood-brain barrier dysfunction.
- Methane Attenuates Hepatic Ischemia/Reperfusion Injury in Rats Through Antiapoptotic, Anti-Inflammatory, and Antioxidative Actions
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