Understanding the tumor immune microenvironment (TIME) for effective therapy
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Summary
By parsing the unique classes and subclasses of tumor immune microenvironment (TIME) that exist within a patient’s tumor, the ability to predict and guide immunotherapeutic responsiveness will improve, and new therapeutic targets will be revealed.
- Type
- review
- Published
- 2018-04-01
- Cited by
- 5,248
- References
- 112
- Access
- Open access
- OpenAlex
- https://openalex.org/W2801309958
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:5056121
Keywords
Tumor microenvironment, Immunotherapy, Immune system, Context (archaeology), Medicine
References
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- Ultraviolet-radiation-induced inflammation promotes angiotropism and metastasis in melanoma
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- Tertiary lymphoid organs in infection and autoimmunity
- Oncogenic Kras-induced GM-CSF production promotes the development of pancreatic neoplasia
- Microenvironmental regulation of tumor progression and metastasis
- Cholesterol, inflammation and innate immunity
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- Tracking Cell Recruitment and Behavior within the Tumor Microenvironment Using Advanced Intravital Imaging Approaches
- CARs versus BiTEs: A Comparison between T Cell-Redirection Strategies for Cancer Treatment.
- Toward Biomaterials for Enhancing Immune Checkpoint Blockade Therapy
- The Neutrophil-Lymphocyte Ratio Is an Independent Prognostic Factor for Overall Survival in Hispanic Patients with Gastric Adenocarcinoma
- The ambitious role of anti angiogenesis molecules: Turning a cold tumor into a hot one.
- Prognostic role of neutrophil-to-lymphocyte ratio and platelet-to-lymphocyte ratio in patients with bone metastases
- Immunomodulatory effects of BRAF and MEK inhibitors: Implications for Melanoma therapy
- Turn Back the TIMe: Targeting Tumor Infiltrating Myeloid Cells to Revert Cancer Progression
- T cells in solid tumors : investigating the immunomodulation in the tumor microenvironment
- Intrahepatic Cholangiocarcinoma: Continuing Challenges and Translational Advances
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- Tumor immune microenvironment: sanctuary of tumor and target for immunotherapy
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