Spatiotemporal dynamics of intratumoral immune cells reveal the immune landscape in human cancer.
Explore this paper's citation graph
Summary
The immune landscape in human colorectal cancer is revealed and the major hallmarks of the microenvironment associated with tumor progression and recurrence are revealed.
- Type
- article
- Published
- 2013-10-17
- Cited by
- 3,797
- References
- 60
- Access
- Open access
- OpenAlex
- https://openalex.org/W1966107523
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:330575
Keywords
Biology, Immune system, Cancer, Dynamics (music), Immune escape
References
- Effector memory T cells, early metastasis, and survival in colorectal cancer.
- Modeling and simulation of the immune system as a self-regulating network.
- Cancer immunosurveillance and immunoediting: the roles of immunity in suppressing tumor development and shaping tumor immunogenicity.
- Helper B Cells Promote Cytotoxic T Cell Survival and Proliferation Independently of Antigen Presentation through CD27/CD70 Interactions1
- Identification of T Cell-Restricted Genes, and Signatures for Different T Cell Responses, Using a Comprehensive Collection of Microarray Datasets1
- IFNγ and lymphocytes prevent primary tumour development and shape tumour immunogenicity
- On the statistical assessment of classifiers using DNA microarray data
- Cancer Statistics, 2006
- The continuum of cancer immunosurveillance: prognostic, predictive, and mechanistic signatures.
- Generation of follicular helper T cells is mediated by IL-21 but independent of TH1, TH2 or TH17 lineages
- The development and fate of follicular helper T cells defined by an IL-21 reporter mouse
- Early Th1 Cell Differentiation Is Marked by A Tfh-like Cell Transition
- Cancer Immunoediting: Integrating Immunity’s Roles in Cancer Suppression and Promotion
- Systems biology of innate immunity.
- Effector and regulatory B cells: modulators of CD4+ T cell immunity
- Confidence intervals for the effect of a prognostic factor after selection of an ‘optimal’ cutpoint
- T follicular helper cell diversity and plasticity
- Overexpression of IL‐21 promotes massive CD8+ memory T cell accumulation
- The good, the bad and the ugly — TFH cells in human health and disease
- Human B cell-attracting chemokine 1 (BCA-1; CXCL13) is an agonist for the human CXCR3 receptor.
Cited by
- Non-Inflammasome Forming NLRs in Inflammation and Tumorigenesis
- Tertiary Lymphoid Structure-Associated B Cells are Key Players in Anti-Tumor Immunity
- Cancer immune contexture and immunotherapy.
- Comprehensive Immune Profiling of Lung Adenocarcinomas Reveals Four Immunosubtypes with Plasma Cell Subtype a Negative Indicator
- PDL1 expression is a poor-prognosis factor in soft-tissue sarcomas
- Identifying baseline immune-related biomarkers to predict clinical outcome of immunotherapy
- Footprints of Sepsis Framed Within Community Acquired Pneumonia in the Blood Transcriptome
- Preoperative systemic immune-inflammation index predicts prognosis of patients with oral squamous cell carcinoma after curative resection
- Immune-related miRNA signature identifies prognosis and immune landscape in head and neck squamous cell carcinomas
- More than a scaffold: Stromal modulation of tumor immunity.
- Prognostic and predictive value of NanoString-based immune-related gene signatures in a neoadjuvant setting of triple-negative breast cancer: relationship to tumor-infiltrating lymphocytes
- Tumor antigen-specific CD4+ T cells in cancer immunity: from antigen identification to tumor prognosis and development of therapeutic strategies.
- The Immune Microenvironment: A Major Player in Human Cancers
- Neutrophil to lymphocyte ratio predicts pattern of recurrence in patients undergoing liver resection for colorectal liver metastasis and thus the overall survival
- Elucidating drivers of oral epithelial dysplasia formation and malignant transformation to cancer using RNAseq
- Mouse models of colorectal cancer as preclinical models
- Therapeutics targeting innate immune/inflammatory responses through the interleukin-6/JAK/STAT signal transduction pathway in patients with cancer.
- Characterization of tumor-associated B-cell subsets in patients with colorectal cancer
- Emerging cytokine networks in colorectal cancer
- Towards the introduction of the ‘Immunoscore’ in the classification of malignant tumours
Related papers
- Research Progress of Immune Cell Function in Patients with Recurrent Genital Herpes
- Probiotics Mechanism of Action on Immune Cells and Beneficial Effects on Human Health
- Effect of stress on immune function, allergy, and health
- Prostaglandins and the immune response.
- Trade‐offs within the immune systems of female White‐footed Mice, Peromyscus leucopus
- Strategies for tumor immune escape.
- Immune Escape Mechanism of Cancer
- AIDS: Escape from the immune system