Genomic Signatures of Selective Pressures and Introgression from Archaic Hominins at Human Innate Immunity Genes.

Keywords

Biology, Innate immune system, Genome, Gene, Acquired immune system

References

• Evolution of the TIR domain-containing adaptors in humans: swinging between constraint and adaptation.喜代美 多田羅, 俊一郎 藤本 — 2011
• Balancing Selection Is the Main Force Shaping the Evolution of Innate Immunity Genes1Anna Ferrer-Admetlla, Elena Bosch, Martin Sikora — 2008
• Life‐threatening infectious diseases of childhood: single‐gene inborn errors of immunity?Alexandre Alcaïs, Lluís Quintana‐Murci, David S. Thaler — 2010
• Human genome variability, natural selection and infectious diseases.Matteo Fumagalli, Manuela Sironi — 2014
• Natural selection on protein-coding genes in the human genomeCarlos D. Bustamante, Adi Fledel-Alon, Scott Williamson — 2005
• Signatures of Environmental Genetic Adaptation Pinpoint Pathogens as the Main Selective Pressure through Human EvolutionMatteo Fumagalli, Manuela Sironi, Uberto Pozzoli — 2011
• Variation in the human immune system is largely driven by non-heritable influencesPetter Brodin, Vladimir Jojic, Tianxiang Gao — 2015
• Natural selection and infectious disease in human populationsElinor K. Karlsson, Dominic Kwiatkowski, Pardis C. Sabeti — 2014
• Human genetic susceptibility to infectious diseaseS. Jonathan Chapman, Adrian V. S. Hill — 2012
• Genome-wide association study identifies variants associated with progression of liver fibrosis from HCV infection.Étienne Patin, Zoltán Kutalik, Julien Guergnon — 2012
• Genetic history of an archaic hominin group from Denisova Cave in SiberiaDavid Reich, Richard E. Green, Martin Kircher — 2010
• Cytoadherence, pathogenesis and the infected red cell surface in Plasmodium falciparum.Chris Newbold, Alister Craig, Sue Kyes — 1999
• Inborn errors of human STAT1: allelic heterogeneity governs the diversity of immunological and infectious phenotypesStéphanie Boisson‐Dupuis, Xiao‐Fei Kong, Satoshi Okada — 2012
• IFITM Proteins Mediate the Innate Immune Response to Influenza A H1N1 Virus, West Nile Virus and Dengue VirusAbraham L. Brass, I‐Chueh Huang, Yair Benita — 2009
• A Composite of Multiple Signals Distinguishes Causal Variants in Regions of Positive SelectionSharon R. Grossman, Ilya Shylakhter, Elinor K. Karlsson — 2010
• Human TLR1 Deficiency Is Associated with Impaired Mycobacterial Signaling and Protection from Leprosy Reversal ReactionElizabeth Ann Misch, Murdo Macdonald, Chaman Ranjit — 2008
• Population genetic tools to dissect innate immunity in humansLluís Quintana‐Murci, Andrew G. Clark — 2013
• Innate Immune Activity Conditions the Effect of Regulatory Variants upon Monocyte Gene ExpressionBenjamin P. Fairfax, Peter Humburg, Seiko Makino — 2014
• A haplotype at STAT2 Introgressed from neanderthals and serves as a candidate of positive selection in Papua New Guinea.Fernando L. Méndez, Joseph C. Watkins, Michael F. Hammer — 2012
• A Map of Recent Positive Selection in the Human GenomeBenjamin F. Voight, Sridhar Kudaravalli, Xiaoquan Wen — 2006

Cited by

• Defining biological subsets in systemic lupus erythematosus: progress toward personalized therapyFrancisco José Muñoz Conde — 2017
• Fine scale mapping of genomic introgressions within the Drosophila yakuba cladeWeb Administrator — 2017
• Evidence that RNA viruses drove of adaptive introgression between Neanderthals and modern humansMaquard Smith — 2018
• Toll‐like receptor polymorphism in host immune response to infectious diseases: A review丸木 一成, 小林 雅彦 — 2019
• TLRs of Our Fathers.Mihai G. Netea, Leo A. B. Joosten — 2016
• Hybridization and endangered species protection in the molecular eraRobert K. Wayne, H. Bradley Shaffer — 2016
• Admixture into and within sub-Saharan AfricaGeorge Busby, Gavin Band, Si Quang Le — 2016
• An evolutionary medicine perspective on Neandertal extinctionAlexis Sullivan, Marc de Manuel, Tomàs Marquès‐Bonet — 2016
• Adaptively introgressed Neandertal haplotype at the OAS locus functionally impacts innate immune responses in humansAaron J. Sams, Anne Dumaine, Yohann Nédélec — 2016
• Genetic determinants of the gut microbiome in UK TwinsJulia K. Goodrich, Emily Davenport, Michelle Beaumont — 2016
• Genetic and epigenetic variation of human populations: An adaptive tale.Lluís Quintana‐Murci — 2016
• The Assimilation Model of modern human origins in light of current genetic and genomic knowledgeFred H. Smith, James C. M. Ahern, Ivor Janković — 2017
• Complex interplay between neutral and adaptive evolution shaped differential genomic background and disease susceptibility along the Italian peninsulaMarco Sazzini, Guido Alberto Gnecchi‐Ruscone, Cristina Giuliani — 2016
• Exome and genome sequencing for inborn errors of immunityIsabelle Meyts, Barbara Bosch, Alexandre Bolze — 2016
• Integrating the signatures of demic expansion and archaic introgression in studies of human population genomicsLauren A. Sugden, Sohini Ramachandran — 2016
• Genetic Adaptation and Neandertal Admixture Shaped the Immune System of Human PopulationsHélène Quach, Maxime Rotival, Julien Pothlichet — 2016
• Signatures of Archaic Adaptive Introgression in Present-Day Human PopulationsFernando Racimo, Davide Marnetto, Emilia Huerta‐Sánchez — 2016
• Genetic Ancestry and Natural Selection Drive Population Differences in Immune Responses to Pathogens.Yohann Nédélec, Joaquín Sanz, Golshid Baharian — 2016
• Survey of Global Genetic Diversity Within the Drosophila Immune SystemAngela M. Early, J. Roman Arguello, Margarida Cardoso-Moreira — 2016
• Archaic hominin admixture facilitated adaptation to Out-of-Africa environmentsRachel M. Gittelman, Joshua G. Schraiber, Benjamin Vernot — 2016

Related papers

• 15 years of introgression studies: quantifying gene flow across EukaryotesAndrius J. Dagilis, David Peede, Jenn M. Coughlan — 2021
• Molecular cytogenetics of introgressive hybridization in plants.Kesara Anamthawat-Jónsson — 2001
• Molecular cytogenetics of introgressive hybridization in plantsKesara Anamthawat‐Jónsson — 2001
• Genetic Introgression Between Different Groups Reveals the Differential Process of Asian cultivated RiceHao Gong, Bin Han — 2021
• Genetic introgression between different groups reveals the differential process of Asian cultivated riceHao Gong, Bin Han — 2021
• Introgressive hybridization in fishes: the biochemical evidenceE. Verspoor, J. Hammart — 1991
• Introgression in maizePaul C. Mangelsdorf — 1961
• Genetic introgression from commercial European pigs to the indigenous Chinese Lijiang breed and associated changes in phenotypesRuifei Yang, Siqi Jin, Suyun Fang — 2024
• Asymmetric Introgressive Hybridization Among Louisiana Iris SpeciesMichael L. Arnold, Shunxue Tang, Steven J. Knapp — 2010
• Genome-Wide Analysis Reveals Human-Mediated Introgression from Western Pigs to Indigenous Chinese BreedsJue Wang, Chengkun Liu, Jie Chen — 2020