The landscape of histone modifications across 1% of the human genome in five human cell lines.
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Summary
High-resolution maps are generated of the functional relationship among histone modifications and gene expression in human cells and identify differences in the histone modification profiles associated with transcriptional differences between the cell lines.
- Type
- article
- Published
- 2007-06-01
- Cited by
- 452
- References
- 60
- Access
- Open access
- OpenAlex
- https://openalex.org/W2122609635
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:10510870
Keywords
H3K4me3, Histone, Biology, Histone H3, Acetylation
References
- Close sequence comparisons are sufficient to identify human cis-regulatory elements.
- Analysis of genome-wide histone acetylation state and enzyme binding using DNA microarrays.
- Histone acetylation in chromatin structure and transcription
- Bioinformatics and Computational Biology Solutions Using R and Bioconductor
- Non-coding RNA.
- Methylation of histone H3 lysine 9 creates a binding site for HP1 proteins
- Antisense Transcription in the Mammalian Transcriptome
- A bivalent chromatin structure marks key developmental genes in embryonic stem cells.
- The diverse functions of histone lysine methylation
- Global and Hox-specific roles for the MLL1 methyltransferase.
- Computational detection and location of transcription start sites in mammalian genomic DNA.
- Histone acetylation and deacetylation in yeast
- Genomic maps and comparative analysis of histone modifications in human and mouse.
- Role of Histone H3 Lysine 27 Methylation in Polycomb-Group Silencing
- Active genes are tri-methylated at K4 of histone H3
- Histone H3 lysine 9 methylation and HP1gamma are associated with transcription elongation through mammalian chromatin.
- Histone H3 lysine 4 methylation patterns in higher eukaryotic genes
- WDR5 associates with histone H3 methylated at K4 and is essential for H3 K4 methylation and vertebrate development.
- Do protein motifs read the histone code?
- The putative oncogene GASC1 demethylates tri- and dimethylated lysine 9 on histone H3
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- The Cardiac Transcription Network Modulated by Gata4, Mef2a, Nkx2.5, Srf, Histone Modifications, and MicroRNAs
- Effects of deranged metabolism on epigenetic changes in cancer
- A Point Mutation in a lincRNA Upstream of GDNF Is Associated to a Canine Insensitivity to Pain: A Spontaneous Model for Human Sensory Neuropathies
- Global H4 acetylation analysis by ChIP-chip in SLE monocytes
- Rôle de la protéine Damaged DNA Binding 2 dans la réponse des cellules tumorales mammaires aux agents thérapeutiques
- Computational biology approaches for studying gene regulatory network discovery and modelling
- Identification of epigenomic patterns to annotate regulatory elements in the human genome
- Multi-layered model of individual HIV infection progression and mechanisms of phenotypical expression
- Cellular Adaptation of Macrophages to Anthrax Lethal Toxin-Induced Pyroptosis via Epigenetic Mechanisms
- RHODOCOCCUS EQUI INFECTION AND INTERFERON-GAMMA REGULATION IN FOALS
- Complexity and high-end computing in biology and medicine.
- Multiple Sites of Type II Site Ligand (Luteolin and BMHPC) Regulation of Gene Expression in PC-3 Cells
- RSV-Induced H3K4 Demethylase KDM5B Leads to Regulation of Dendritic Cell-Derived Innate Cytokines and Exacerbates Pathogenesis In Vivo
- Genetic-epigenetic interactions in medulloblastoma development
- Characterization of Interleukin 10 gene variations and serum levels as predictive factors for the clinical outcome of Non-Hodgkin Lymphoma patients and Analysis of molecular mechanisms of Interleukin 10 gene regulation in B cells
- Determinants of Embryonic Hematopoietic Stem Cell Emergence and Maturation
- H4K16 acetylation during embryonic stem cell differentiation
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