Histone H3 lysine 9 methylation and HP1gamma are associated with transcription elongation through mammalian chromatin.

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Summary

It is shown that H3K9 di- and trimethylation occur in the transcribed region of active genes in mammalian chromatin and this modification is dynamic, as it increases during activation of transcription and is rapidly removed upon gene repression.

Type
article
Published
2005-08-05
Cited by
738
References
49
Access
Open access

Keywords

Biology, EZH2, Euchromatin, Histone methylation, Heterochromatin protein 1

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