Histone H3 lysine 9 methylation and HP1gamma are associated with transcription elongation through mammalian chromatin.
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Summary
It is shown that H3K9 di- and trimethylation occur in the transcribed region of active genes in mammalian chromatin and this modification is dynamic, as it increases during activation of transcription and is rapidly removed upon gene repression.
- Type
- article
- Published
- 2005-08-05
- Cited by
- 738
- References
- 49
- Access
- Open access
- OpenAlex
- https://openalex.org/W2026501344
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:27927878
Keywords
Biology, EZH2, Euchromatin, Histone methylation, Heterochromatin protein 1
References
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- GATA-1-dependent transcriptional repression of GATA-2 via disruption of positive autoregulation and domain-wide chromatin remodeling
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Cited by
- Identification and Characterization of Novel Sir3/MeCP2-Chromatin Interactions
- Leaving a mark: the many footprints of the elongating RNA polymerase II.
- Unique and redundant functions of C. elegans HP1 proteins in post-embryonic development.
- Remodeling of higher order chromatin structure by the JIL-1 histone H3 kinase in Drosophila
- The emerging functions of histone demethylases.
- PR-Set7 Establishes a Repressive trans-Tail Histone Code That Regulates Differentiation
- Chromodomain-mediated spreading on active genes
- Impact of DNA demethylation of the G0S2 gene on the transcription of G0S2 in squamous lung cancer cell lines with or without nuclear receptor agonists.
- Regulation of alternative splicing by local histone modifications: potential roles for RNA-guided mechanisms
- The three-dimensional genome: regulating gene expression during pluripotency and development
- MiR‐302 enhances the viability and stemness of male germline stem cells
- Regulation and function of H3K9 methylation.
- Chromatin in embryonic stem cell neuronal differentiation.
- Proteínas de unión a DNA metilado y cáncer: familia MBD (Methyl-CpG Binding Domain)
- Dynamic histone modifications at the promoters of Hox genes in embryonic stem cells
- Epigenetic analysis of promiscuous gene expression in central tolerance
- Functional studies of RNA polymerase II-dependent transcription in yeast Saccharomyces cerevisiae
- H3K9/HP1 and Polycomb: two key epigenetic silencing pathways for gene regulation and embryo development.
- Long-term Effects of Severe Sepsis on Dendritic Cell Function.
- The importance of epigenetics in embryonic development and reproductive biotechnology.
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