How mitochondria produce reactive oxygen species
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Summary
The description outlined here facilitates the understanding of factors that favour mitochondrial ROS production and develops better methods to measure mitochondrial O2•− and H2O2 formation in vivo, as uncertainty about these values hampers studies on the role of mitochondrial ROS in pathological oxidative damage and redox signalling.
- Type
- review
- Published
- 2008-12-12
- Cited by
- 7,639
- References
- 134
- Access
- Open access
- OpenAlex
- https://openalex.org/W2122341467
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:7977231
Keywords
Mitochondrion, NAD+ kinase, Mitochondrial matrix, Superoxide, Reactive oxygen species
References
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- Elevated mitochondrial superoxide contributes to enhanced chemoreflex in heart failure rabbits.
- The electron transfer flavoprotein: ubiquinone oxidoreductases.
- Brain superoxide anion formation in immature rats during seizures: protection by selected compounds.
- Cardiac mitochondrial network excitability: insights from computational analysis.
- Grateloupia lanceolata (Okamura) Kawaguchi, the Edible Red Seaweed, Inhibits Lipid Accumulation and Reactive Oxygen Species Production During Differentiation in 3T3‐L1 Cells
- Dietary supplementation with N-acetyl cysteine, α-tocopherol and α-lipoic acid reduces the extent of oxidative stress and proinflammatory state in aged rat brain
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- Respiratory chain complex II as general sensor for apoptosis.
- Calcium, Bioenergetics, and Neuronal Vulnerability in Parkinson's Disease*
- Purified acetaminophen-glutathione conjugate is able to induce oxidative stress in rat liver mitochondria.
- Mitochondrial DNA Oxidative Damage and Repair in Aging and Alzheimer's Disease
- The Role of Mechanical Force and ROS in Integrin-Dependent Signals
- Cardiac Metabolism in Heart Failure - Implications beyond ATP production
- miR-210: Fine-Tuning the Hypoxic Response
- In vivo single cell detection of metabolic oscillations in stem cells
- Mitochondrially Targeted Vitamin E Succinate Modulates Expression of Mitochondrial DNA Transcripts and Mitochondrial Biogenesis
- Polyphyletic origins of schizothoracine fish (Cyprinidae, Osteichthyes) and adaptive evolution in their mitochondrial genomes.
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