Hybrid restriction enzymes: zinc finger fusions to Fok I cleavage domain.

Explore this paper's citation graph

Summary

The deliberate creation of novel site-specific endonucleases by linking two different zinc finger proteins to the cleavage domain of Fok I endonuclease and the zinc finger motifs opens the way to generate many new enzymes with tailor-made sequence specificities desirable for various applications.

Type
article
Published
1996-02-06
Cited by
1,990
References
24
Access
Open access

Keywords

Restriction enzyme, Zinc finger, Recognition sequence, Zinc finger nuclease, Nuclease

References

Cited by

Related papers