Basic and therapeutic aspects of angiogenesis.

Michael Potente, Holger Gerhardt, Peter Carmeliet · Cell · 2011

Summary

The emerging principles of vascular growth provide exciting new perspectives, the translation of which might overcome the current limitations of pro- and antiangiogenic medicine.

Type: review
Published: 2011-09-16
Cited by: 2,691
References: 100
Access: Open access
DOI: https://doi.org/10.1016/j.cell.2011.08.039
PubMed: https://pubmed.ncbi.nlm.nih.gov/21925313/
OpenAlex: https://openalex.org/W2074196937
Semantic Scholar: https://api.semanticscholar.org/CorpusID:6413832

Keywords

Biology, Angiogenesis, Therapeutic angiogenesis, Computational biology, Cancer research

References

Arterial–Venous Specification During DevelopmentDustin Homan — 2009
Vascular development: genetic mechanisms and links to vascular disease.John C. Chappell, Victoria L. Bautch — 2010
Notch signaling in the vasculatureThomas Gridley — 2010
Endogenous inhibitors of angiogenesis.Christiana Ruhrberg — 2001
Migratory neighbors and distant invaders: tumor-associated niche cells.Jared Wels, Rosandra N. Kaplan, Shahin Rafii — 2008
Pathways mediating VEGF-independent tumor angiogenesis.Napoleone Ferrara — 2010
Mechanisms of Vessel Branching: Filopodia on Endothelial Tip Cells Lead the WayFrederik De Smet, Inmaculada Segura, Katrien De Bock — 2009
Tumor and stromal pathways mediating refractoriness/resistance to anti-angiogenic therapies.Yongping Crawford, Napoleone Ferrara — 2009
Ephrin-B2 controls VEGF-induced angiogenesis and lymphangiogenesisYingdi Wang, Masanori Nakayama, Mara E. Pitulescu — 2010
The Delta paradox: DLL4 blockade leads to more tumour vessels but less tumour growthGavin Thurston, Irene Noguera‐Troise, George D. Yancopoulos — 2007
Ephrin-B2 regulates VEGFR2 function in developmental and tumour angiogenesisSuphansa Sawamiphak, Sascha Seidel, Clara L. Essmann — 2010
Targeting the ANG2/TIE2 axis inhibits tumor growth and metastasis by impairing angiogenesis and disabling rebounds of proangiogenic myeloid cells.Roberta Mazzieri, Ferdinando Pucci, Davide Moi — 2011
Tumor angiogenesis: therapeutic implications.Louis M. Sherwood, Edith E. Parris, Judah Folkman — 1971
Tipping the Balance: Robustness of Tip Cell Selection, Migration and Fusion in AngiogenesisKatie Bentley, Giovanni Mariggi, Holger Gerhardt — 2009
VEGF inhibition: insights from preclinical and clinical studiesYongping Crawford, Napoleone Ferrara — 2008
Molecular regulation of angiogenesis and lymphangiogenesisRalf H. Adams, Kari Alitalo — 2007
Arterial/Venous Segregation by Selective Cell Sprouting: An Alternative Mode of Blood Vessel FormationShane P. Herbert, Jan Huisken, Tyson N. Kim — 2009
Angiopoietin-1 is essential in mouse vasculature during development and in response to injury.Marie Jeansson, Alexander Gawlik, Gregory A. Anderson — 2011
Molecular mechanisms and clinical applications of angiogenesisPeter Carmeliet, Rakesh K. Jain — 2011
Intussusceptive angiogenesis and its role in vascular morphogenesis, patterning, and remodelingAndrew N. Makanya, Ruslan Hlushchuk, Valentin Djonov — 2009

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Inhibition of Notch signaling leads to increased intracellular ROS by up-regulating Nox4 expression in primary HUVECs.Antonio Ansón Anadón — 2014
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Basic and therapeutic aspects of angiogenesis.

Summary

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