Microglia–blood vessel interactions: a double-edged sword in brain pathologies
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Summary
The current state of the art of the causes and mechanisms of pathological interactions between microglia and blood vessels are presented and the possibilities of targeting those dysfunctional interactions for the development of future therapeutics are explored.
- Type
- article
- Published
- 2016-03-01
- Cited by
- 261
- References
- 203
- Access
- Open access
- OpenAlex
- https://openalex.org/W26711460
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:10271276
Keywords
Icon, Sustainability, Political science, Public administration, Computer science
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Cited by
- Nanotherapy for Alzheimer's disease and vascular dementia: Targeting senile endothelium.
- Plasma Hemopexin ameliorates murine spinal cord injury by switching microglia from the M1 state to the M2 state
- Stage-Specific Immune Dysregulation in Multiple Sclerosis
- Cellular response of the blood-brain barrier to injury: Potential biomarkers and therapeutic targets for brain regeneration.
- Making Ends Meet: Myeloid Cells Catalyze Blood Vessel Repair in the Brain.
- Defining differential roles for microglia and infiltrating macrophages in the growth and neovascularization of glioma
- Glial Dysfunction and Blood-Brain Barrier Impairment in the Developing Brain
- Microglia and brain macrophages: An update
- The Translational Significance of the Neurovascular Unit*
- Brain Barrier Breakdown as a Cause and Consequence of Neuroinflammation in Sepsis
- Microglia preconditioned by oxygen-glucose deprivation promote functional recovery in ischemic rats
- Zika Virus Infects Human Fetal Brain Microglia and Induces Inflammation
- Oral administration of corticosterone at stress-like levels drives microglial but not vascular disturbances post-stroke.
- Traumatic brain injury results in acute rarefication of the vascular network
- Long-Term Kinetics of Immunologic Components and Neurological Deficits in Rats Following Repetitive Mild Traumatic Brain Injury
- Resilience and Vulnerability to Pain and Inflammation in the Hippocampus
- Triggering Receptor Expressed on Myeloid Cells 2, a Novel Regulator of Immunocyte Phenotypes, Confers Neuroprotection by Relieving Neuroinflammation
- Genetic deletion of P-glycoprotein alters stress responsivity and increases depression-like behavior, social withdrawal and microglial activation in the hippocampus of female mice.
- TRPC Channels and Brain Inflammation.
- Microglia: Housekeeper of the Central Nervous System