Using Affinity To Provide Long-Term Delivery of Antiangiogenic Drugs in Cancer Therapy.
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Summary
It was shown that affinity-based cyclodextrin polymers loaded with silibinin showed substantially longer release rates than nonaffinity control polymers; however, both were capable of inhibiting tumor growth in the time frame studied.
- Type
- article
- Published
- 2017-02-09
- Cited by
- 15
- References
- 39
- Access
- Open access
- OpenAlex
- https://openalex.org/W28128564
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:11930547
Keywords
Art
References
- Local delivery of angiogenesis-inhibitor minocycline combined with radiotherapy and oral temozolomide chemotherapy in 9L glioma.
- Small-molecule library screening by docking with PyRx.
- Neurosurgical Management and Prognosis of Patients With Glioblastoma That Progresses During Bevacizumab Treatment
- Tranilast inhibits the proliferation, chemotaxis and tube formation of human microvascular endothelial cells in vitro and angiogenesis in vivo
- Gliadel wafers in the treatment of malignant glioma: a systematic review
- Design of Cyclodextrin-Based Photopolymers with Enhanced Molecular Recognition Properties: A Template-Free High-Throughput Approach
- Solvation and dynamic behavior of cyclodextrins in dimethyl sulfoxide solution.
- Anticancer polymeric nanomedicine bearing synergistic drug combination is superior to a mixture of individually-conjugated drugs.
- Capping of Silybin with β-Cyclodextrin Influences its Binding with Bovine Serum Albumin: A Study by Fluorescence Spectroscopy and Molecular Modeling
- Silibinin strongly inhibits growth and survival of human endothelial cells via cell cycle arrest and downregulation of survivin, Akt and NF-κB: implications for angioprevention and antiangiogenic therapy
- Polymeric implants for cancer chemotherapy.
- Silibinin inhibits angiogenesis via Flt-1, but not KDR, receptor up-regulation.
- Anti-angiogenic therapy for cancer: current progress, unresolved questions and future directions
- Thermodynamics of molecular recognition by cyclodextrins. 1. Calorimetric titration of inclusion complexation of naphthalenesulfonates with .alpha.-, .beta.-, and .gamma.-cyclodextrins: enthalpy-entropy compensation
- Local delivery of temozolomide by biodegradable polymers is superior to oral administration in a rodent glioma model
- Angiogenesis in Gliomas: Imaging and Experimental Therapeutics
- Complexation Thermodynamics of Cyclodextrins.
- Adjustable release of mitomycin C for inhibition of scar tissue formation after filtration surgery
- Experimental Studies and Modeling of Drug Release from a Tunable Affinity-Based Drug Delivery Platform
- Silibinin inhibits colorectal cancer growth by inhibiting tumor cell proliferation and angiogenesis.
Cited by
- Use of nanoparticles for glioblastoma treatment: a new approach.
- Self-assembly of affinity-controlled nanoparticles via host-guest interactions for drug delivery.
- Combining Cellulose and Cyclodextrins: Fascinating Designs for Materials and Pharmaceutics
- Cyclodextrin polymer preserves sirolimus activity and local persistence for anti-fibrotic delivery over the time course of wound healing
- Tunable Engineering of Heparinized Injectable Hydrogels for Affinity‐Based Sustained Delivery of Bioactive Factors
- Serum Biomolecules Unable to Compete with Drug Refilling into Cyclodextrin Polymers Regardless of Form
- Affinity-based polymers provide long-term immunotherapeutic drug delivery across particle size ranges optimal for macrophage targeting
- Engineering Selective Molecular Tethers to Enhance Suboptimal Drug Properties
- Affinity Effects on the Release of Non-Conventional Antifibrotics from Polymer Depots
- Leveraging Affinity Interactions to Prolong Drug Delivery of Protein Therapeutics
- Advancements in cyclodextrin-based controlled drug delivery: Insights into pharmacokinetic and pharmacodynamic profiles
- Treating glioblastoma with dextrin-based polymers
- Cyclodextrins-based hydrogel
- Impact of Cyclodextrin in Drug Delivery System
- Decoding Cyclodextrins in Skin Applications: Structure, Mechanisms, and Safety in Cosmetic and Dermatologic Formulations (Part I)
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