Protumor and antitumor functions of neutrophil granulocytes
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Summary
This work proposes a model in which homeostatic chronic recruitment and activation of neutrophils result in mainly protumor activity, which may offer new possibilities in biologic therapy of cancer.
- Type
- review
- Published
- 2013-03-01
- Cited by
- 153
- References
- 129
- OpenAlex
- https://openalex.org/W2070818071
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:12305471
Keywords
Immunology, Biology, Effector, Cancer, Inflammation
References
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- Neutrophil-derived proteins: selling cytokines by the pound.
- Increased Production of Immature Myeloid Cells in Cancer Patients: A Mechanism of Immunosuppression in Cancer1
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- Fas Ligand Engagement of Resident Peritoneal Macrophages In Vivo Induces Apoptosis and the Production of Neutrophil Chemotactic Factors1
- Proinflammatory Activities of S100: Proteins S100A8, S100A9, and S100A8/A9 Induce Neutrophil Chemotaxis and Adhesion 1
- Still Benched on its Way to the Bedside: Sphingosine Kinase 1 as an Emerging Target in Cancer Chemotherapy
- The Prognostic Value of Tumor-Infiltrating Neutrophils in Gastric Adenocarcinoma after Resection
- Infiltrating neutrophils mediate the initial angiogenic switch in a mouse model of multistage carcinogenesis
- Neutrophil Chemokines Secreted by Tumor Cells Mount a Lung Antimetastatic Response during Renal Cell Carcinoma Progression
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- G-CSF: function and modes of action (Review).
- NOD-like receptors and the innate immune system: coping with danger, damage and death.
- Fas ligand exerts its pro‐inflammatory effects via neutrophil recruitment but not activation
Cited by
- Pattern-recognition receptors and neutrophils in cancer inflammation
- Neutrophil and Lymphocyte Counts as Clinical Markers for Stratifying Low-Risk Prostate Cancer
- CD11b+Ly6G+ cells inhibit tumor growth by suppressing IL-17 production at early stages of tumorigenesis
- In vivo evidence that secretion of HLA‐G by immunogenic tumor cells allows their evasion from immunosurveillance
- The kinship of neutrophils and granulocytic myeloid-derived suppressor cells in cancer: cousins, siblings or twins?
- Increased pro-angiogenic factors, infiltrating neutrophils and CD163(+) macrophages in bronchoalveolar lavage fluid from lung cancer patients.
- The Association of Immune Cell Infiltration and Prognosis in Colorectal Cancer
- Granulocyte functions are independent of arginine availability
- Immunomonitoring and prognostic relevance of neutrophils in clinical trials.
- The Multifaceted Roles Neutrophils Play in the Tumor Microenvironment
- Neutrophil-mediated tumour angiogenesis: subversion of immune responses to promote tumour growth.
- AHNAK and Inflammatory Markers Predict Poor Survival in Laryngeal Carcinoma
- NETosis: a new factor in tumor progression and cancer-associated thrombosis
- Social networking of human neutrophils within the immune system.
- Neutrophil-Lymphocyte Ratio and Pathological Response to Neoadjuvant Chemotherapy in Patients With Muscle-Invasive Bladder Cancer.
- On the cytokines produced by human neutrophils in tumors.
- Modulation of neutrophil granulocytes in the tumor microenvironment: mechanisms and consequences for tumor progression.
- Neutrophil extracellular traps in cancer progression
- Tumor-associated neutrophils stimulate T cell responses in early-stage human lung cancer.
- Diabetes mellitus and the neutrophil to lymphocyte ratio predict overall survival in non-viral hepatocellular carcinoma treated with transarterial chemoembolization
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