HSV-1 strain McKrae is more neuroinvasive than HSV-1 KOS after corneal or vaginal inoculation in mice
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Summary
KOS and McKrae replicated equivalently after intracranial inoculation, indicating that McKrae’s pathogenic phenotype is linked to neuroinvasiveness rather than neurovirulence.
- Type
- article
- Published
- 2013-01-20
- Cited by
- 42
- References
- 53
- Access
- Open access
- OpenAlex
- https://openalex.org/W2013243191
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:13040817
Keywords
Biology, Virology, Inoculation, Virus, Viral replication
References
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- The Latent Herpes Simplex Virus Type 1 Genome Copy Number in Individual Neurons Is Virus Strain Specific and Correlates with Reactivation
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- American College Health Association Annual Pap Test and Sexually Transmitted Infection Survey: 2006
Cited by
- Novel rat models to study primary genital herpes simplex virus-2 infection
- Single dose of Glycoprotein K (gK)-deleted HSV-1 live-attenuated virus protects mice against lethal vaginal challenge with HSV-1 and HSV-2 and induces lasting T cell memory immune responses
- Deletion of a Predicted β-Sheet Domain within the Amino Terminus of Herpes Simplex Virus Glycoprotein K Conserved among Alphaherpesviruses Prevents Virus Entry into Neuronal Axons
- Herpes simplex virus type 1 (HSV-1) pathogenesis and HSV gene therapy of experimental autoimmune encephalomyelitis
- Viral forensic genomics reveals the relatedness of classic herpes simplex virus strains KOS, KOS63, and KOS79
- Roles of Us8A and Its Phosphorylation Mediated by Us3 in Herpes Simplex Virus 1 Pathogenesis
- Biological features of herpes simplex virus type 1 latency in mice according to experimental conditions and type of neurones.
- Impact of Type I Interferon on the Safety and Immunogenicity of an Experimental Live-Attenuated Herpes Simplex Virus 1 Vaccine in Mice
- Genetic characterization of human herpesvirus type 1: Full-length genome sequence of strain obtained from an encephalitis case from India
- A Model of Genital Herpes Simplex Virus Type 1 Infection in Rhesus Macaques
- Differentiated Human SH-SY5Y Cells Provide a Reductionist Model of Herpes Simplex Virus 1 Neurotropism
- Antibody-based immunotherapy of aciclovir resistant ocular herpes simplex virus infections.
- Modeling the pathology, immune responses, and kinetics of HSV-1 replication in the lip scarification model.
- Experimental Oral Herpes Simplex Virus-1 (HSV-1) Co-infection in Simian Immunodeficiency Virus (SIV)-Infected Rhesus Macaques
- Virus-nucleus interactions in late herpesvirus infection
- Data-Driven Computational Approach to Study Bio-Molecular Interactions
- Elucidating the Role of Senataxin During HSV-1 Infection
- Insights into the pathogenesis of herpes simplex encephalitis from mouse models
- Viral Genetics Modulate Orolabial Herpes Simplex Virus Type 1 Shedding in Humans
- The STING agonist 5,6 dimethylxanthenone-4-acetic acid (DMXAA) stimulates an antiviral state and protects mice against herpes simplex virus-induced neurological disease.
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