Function and regulation of CREB family transcription factors in the nervous system.
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Summary
This review focuses on the current level of understanding of where, when, and how CREB family members function in the nervous system.
- Type
- review
- Published
- 2002-08-15
- Cited by
- 2,174
- References
- 191
- Access
- Open access
- OpenAlex
- https://openalex.org/W2068412840
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:14028417
Keywords
CREB, Neuroscience, Transcription factor, Biology, Effector
References
- Transcriptional attenuation following cAMP induction requires PP-1-mediated dephosphorylation of CREB.
- A cluster of phosphorylation sites on the cyclic AMP-regulated nuclear factor CREB predicted by its sequence
- cAMP Response Element-binding Protein (CREB) Interacts with Transcription Factors IIB and IID (*)
- Regulation of CREB phosphorylation in the suprachiasmatic nucleus by light and a circadian clock.
- Developmentally Regulated NMDA Receptor-Dependent Dephosphorylation of cAMP Response Element-Binding Protein (CREB) in Hippocampal Neurons
- Recombinant cyclic AMP response element binding protein (CREB) phosphorylated on Ser-133 is transcriptionally active upon its introduction into fibroblast nuclei.
- CBP-independent activation of CREM and CREB by the LIM-only protein ACT
- Targeting of the CREB gene leads to up‐regulation of a novel CREB mRNA isoform.
- Multilevel regulation of the circadian clock
- FGF and stress regulate CREB and ATF‐1 via a pathway involving p38 MAP kinase and MAPKAP kinase‐2.
- Direct Evidence for Biphasic cAMP Responsive Element-Binding Protein Phosphorylation during Long-Term Potentiation in the Rat Dentate Gyrus In Vivo
- Nuclear calcium signaling controls CREB-mediated gene expression triggered by synaptic activity
- Three distinct regions within the constitutive activation domain of cAMP regulatory element-binding protein (CREB) are required for transcription activation.
- Cerebellar Defects in Ca2+/Calmodulin Kinase IV-Deficient Mice
- Translocation of calmodulin to the nucleus supports CREB phosphorylation in hippocampal neurons
- Involvement of cAMP-Dependent Protein Kinase in the Nucleus Accumbens in Cocaine Self-Administration and Relapse of Cocaine-Seeking Behavior
- Phosphorylation of cAMP Response Element-Binding Protein in Hippocampal Neurons as a Protective Response after Exposure to Glutamate In Vitro and Ischemia In Vivo
- Different Requirements for cAMP Response Element Binding Protein in Positive and Negative Reinforcing Properties of Drugs of Abuse
- Histone deacetylase inhibitors arrest polyglutamine-dependent neurodegeneration in Drosophila
- The MAPK/ERK Cascade Targets Both Elk-1 and cAMP Response Element-Binding Protein to Control Long-Term Potentiation-Dependent Gene Expression in the Dentate Gyrus In Vivo
Cited by
- Prolactin-induced protein in breast cancer.
- Excitation-Transcription Coupling: Signaling by Ion Channels to the Nucleus
- Cellular and molecular mechanisms of dichlorvos neurotoxicity: cholinergic, nonchlolinergic, cell signaling, gene expression and therapeutic aspects.
- Characterization of fluoxetine plus olanzapine treatment in rats: A behavior, endocrine, and immediate‐early gene expression analysis
- Advances in the production of human therapeutic proteins in yeasts and filamentous fungi
- Cross talk between Ca2+ and redox signalling cascades in muscle and neurons through the combined activation of ryanodine receptors/Ca2+ release channels
- Phosphorylated cAMP response element‐binding protein levels in guinea pig brainstem auditory nuclei after unilateral cochlear ablation
- Intracellular control of developmental and regenerative axon growth
- Evolution of motif variants and positional bias of the cyclic-AMP response element
- Developmental downregulation of histone posttranslational modifications regulates visual cortical plasticity.
- Regulation of neural migration by the CREB/CREM transcription factors and altered Dab1 levels in CREB/CREM mutants.
- Phosphodiesterases in the central nervous system.
- Drosophila Models of Alzheimer's Amyloidosis: The Challenge of Dissecting the Complex Mechanisms of Toxicity of Amyloid-β 42
- Sildenafil protects against 3-nitropropionic acid neurotoxicity through the modulation of calpain, CREB, and BDNF.
- The administration of olanzapine and fluoxetine has synergistic effects on intracellular survival pathways in the rat brain.
- The dorsal striatum expressing adenylyl cyclase-5 controls behavioral sensitivity of the righting reflex to high-dose ethanol.
- Elevated dopamine D2 receptor in prefrontal cortex of CUMS rats is associated with downregulated cAMP-independent signaling pathway.
- Genome-Wide Profiling of the Activity-Dependent Hippocampal Transcriptome
- Current hypotheses on the mechanisms of alcoholism
- ConBr, a lectin from Canavalia brasiliensis seeds, modulates signaling pathways and increases BDNF expression probably via a glycosylated target
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