Direct Evidence for Biphasic cAMP Responsive Element-Binding Protein Phosphorylation during Long-Term Potentiation in the Rat Dentate Gyrus In Vivo
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Summary
The spatial and temporal dynamics of CREB phosphorylation during hippocampal LTP are resolved, showing that the transcription factor CREB is specifically recruited at two distinct time points in some forms of hippocampal synaptic plasticity in vivo.
- Type
- article
- Published
- 1999-07-01
- Cited by
- 155
- References
- 42
- Access
- Open access
- OpenAlex
- https://openalex.org/W1576022142
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:17867669
Keywords
Dentate gyrus, Long-term potentiation, Neuroscience, Phosphorylation, In vivo
References
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- Protein kinase A inhibitors prevent the maintenance of hippocampal long-term potentiation.
- Effects of KN-62, a specific inhibitor of calcium/calmodulin-dependent protein kinase II, on long-term potentiation in the rat hippocampus.
- CREB as a memory modulator: induced expression of a dCREB2 activator isoform enhances long-term memory in Drosophila.
- Injection of the cAMP-responsive element into the nucleus of Aplysia sensory neurons blocks long-term facilitation
- Contrasting properties of two forms of long-term potentiation in the hippocampus
- Design of a multiple slice interface chamber and application for resolving the temporal pattern of CREB phosphorylation in hippocampal long-term potentiation.
- Biotin amplification of biotin and horseradish peroxidase signals in histochemical stains.
- Stimulation of cAMP response element (CRE)-mediated transcription during contextual learning
- Engraftment and development of human T and B cells in mice after bone marrow transplantation.
- 5-HT modulates protein synthesis and the expression of specific proteins during long-term facilitation in Aplysia sensory neurons.
- Inhibition by compactin demonstrates a requirement of isoprenoid metabolism for long-term potentiation in rat hippocampal slices.
- Signaling from synapse to nucleus: postsynaptic CREB phosphorylation during multiple forms of hippocampal synaptic plasticity.
- Memories of NMDA receptors and LTP
- Induction of CRE-mediated gene expression by stimuli that generate long-lasting LTP in area CA1 of the hippocampus.
- Cross talk between ERK and PKA is required for Ca2+ stimulation of CREB-dependent transcription and ERK nuclear translocation.
- CREB phosphorylation and dephosphorylation: a Ca(2+)- and stimulus duration-dependent switch for hippocampal gene expression.
Cited by
- Activation of the dentate gyrus by stimulation of the contralateral perforant pathway: Evoked potentials and long‐term potentiation after ipsi‐ and contralateral induction
- Increased expression, but not postsynaptic localisation, of ionotropic glutamate receptors during the late-phase of long-term potentiation in the dentate gyrus in vivo.
- NMDA Receptors in Drosophila
- The Roles of Nitric Oxide Signaling and cAMP Response Element Binding Protein in Fear Conditioning
- Transcription Factors CREB and NF-KB: Involvement in Synaptic Plasticity and Memory Formation
- Long‐term potentiation in the dentate gyrus of the rat hippocampus is accompanied by brain‐derived neurotrophic factor‐induced activation of TrkB
- Plastic processes in the dentate gyrus: a computational perspective.
- Focal Adhesion Kinase Is Required, But Not Sufficient, for the Induction of Long-Term Potentiation in Dentate Gyrus Neurons In Vivo
- Influence of gender and social environment in an animal model of affective disorders: evidence for social support in rats?
- CREB is required for acquisition of ischemic tolerance in gerbil hippocampal CA1 region
- Phosphorylation of cAMP Response Element-Binding Protein in Hippocampal Neurons as a Protective Response after Exposure to Glutamate In Vitro and Ischemia In Vivo
- Morphological Correlates Of Synaptic Plasticity After Long Term Potentiation In The Rat Hippocampus
- The MAPK/ERK Cascade Targets Both Elk-1 and cAMP Response Element-Binding Protein to Control Long-Term Potentiation-Dependent Gene Expression in the Dentate Gyrus In Vivo
- Induction and Experience-Dependent Consolidation of Stable Long-Term Potentiation Lasting Months in the Hippocampus
- Cyclical changes in endogenous levels of oestrogen modulate the induction of LTD and LTP in the hippocampal CA1 region
- CREB in adult neurogenesis – master and partner in the development of adult‐born neurons?
- Muscarinic receptor‐mediated phosphorylation of cyclic AMP response element binding protein in human neuroblastoma cells
- Interaction of dopamine D1 and NMDA receptors mediates acute clozapine potentiation of glutamate EPSPs in rat prefrontal cortex.
- Reinforcement of rat hippocampal LTP by holeboard training.
- dCREB2-Mediated Enhancement of Memory Formation
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