Chemical Chaperones Reduce ER Stress and Restore Glucose Homeostasis in a Mouse Model of Type 2 Diabetes

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Summary

It is demonstrated that chemical chaperones enhance the adaptive capacity of the ER and act as potent antidiabetic modalities with potential application in the treatment of type 2 diabetes.

Type
article
Published
2006-08-25
Cited by
2,453
References
13
Access
Open access

Keywords

Unfolded protein response, Type 2 diabetes, Endoplasmic reticulum, Internal medicine, Endocrinology

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