Focal adhesion kinase: in command and control of cell motility

Keywords

Focal adhesion, Cell biology, Motility, Cell adhesion, Cytoskeleton

References

• FAK integrates growth-factor and integrin signals to promote cell migrationMaría Pilar Celma Valero — 2000
• The Adaptor Protein Paxillin Is Essential for Normal Development in the Mouse and Is a Critical Transducer of Fibronectin SignalingSmitha Sundaram, B.G. Eldridge — 2002
• Matrix Metalloproteinases and Tissue Inhibitors of Metalloproteinases: Structure, Function, and BiochemistryAngel de Lamorena — 2003
• FAK induces expression of Prx1 to promote tenascin-C–dependent fibroblast migrationJulio Antonio García López, Antonio María Ávila Álvarez, Miguel Ángel Díaz Mier — 2003
• Identification of transcription factor KLF8 as a downstream target of focal adhesion kinase in its regulation of cyclin D1 and cell cycle progression.David G. Schultz — 2003
• Tyrosine phosphorylation of type Iγ phosphatidylinositol phosphate kinase by Src regulates an integrin–talin switchRasmus Hofwimmer, Daniel Skog Lidander — 2003
• Paxillin and focal adhesion signallingChristopher E. Turner — 2000
• Making smarter immunotherapiesMohammad A. A. Ibrahim, Frances Gotch — 2000
• mDia mediates Rho-regulated formation and orientation of stable microtubulesAlexander F. Palazzo, Tiffani A. Cook, Arthur S. Alberts — 2001
• Focal adhesion kinase signaling activities and their implications in the control of cell survival and motility.Steven K. Hanks — 2003
• The integrin–actin connection, an eternal love affairCord Brakebusch, Reinhard Fässler — 2003
• Regulation of focal complex composition and disassembly by the calcium-dependent protease calpain.Amit Bhatt, Irina Kaverina, Carol Otey — 2002
• Pyk2 and FAK regulate neurite outgrowth induced by growth factors and integrinsInga Ivanković-Dikić, Eva Grönroos, Andree Blaukat — 2000
• Invadopodia: unique methods for measurement of extracellular matrix degradation in vitro.Emma T. Bowden, Peter J. Coopman, Susette C. Mueller — 2001
• Regulation of the PH-domain-containing tyrosine kinase Etk by focal adhesion kinase through the FERM domainRiyan Chen, Oekyung Kim, Ming Li — 2001
• Induced Focal Adhesion Kinase (FAK) Expression in FAK-Null Cells Enhances Cell Spreading and Migration Requiring Both Auto- and Activation Loop Phosphorylation Sites and Inhibits Adhesion-Dependent Tyrosine Phosphorylation of Pyk2James D. Owen, Paul J. Ruest, David W. Fry — 1999
• Required role of focal adhesion kinase (FAK) for integrin-stimulated cell migration.David J. Sieg, Christof R. Hauck, David D. Schlaepfer — 1999
• v-Src SH3-enhanced Interaction with Focal Adhesion Kinase at β1 Integrin-containing Invadopodia Promotes Cell Invasion*Christof R. Hauck, Datsun A. Hsia, Duško Ilić — 2002
• Integrin engagement suppresses RhoA activity via a c-Src-dependent mechanism.William T. Arthur, Leslie Petch, Keith Burridge — 2000
• The v-Src SH3 Domain Facilitates a Cell Adhesion-independent Association with Focal Adhesion Kinase*Christof R. Hauck, Tony Hunter, David D. Schlaepfer — 2001

Cited by

• Characterization of G protein-coupled estrogen receptor (GPER) in breast epithelial proliferation and morphogenesisAllison L Scaling — 2012
• Signaling endosomes and growth cone motility in axon regeneration.Michael B. Steketee, Jeffrey L. Goldberg — 2012
• Murine lipid phosphate phosphohydrolase-3 acts as a cell-associated integrin ligand.Bahtijar Vogel — 2005
• Steroid receptor coactivator-3, a homolog of Taiman that controls cell migration in the Drosophila ovary, regulates migration of human ovarian cancer cells.Esther Pascua Echegaray — 2005
• Weak Expression of Focal Adhesion Kinase (pp125FAK) in Patients with Cervical Cancer Is Associated with Poor Disease OutcomeBoris Gabriel, Axel zur Hausen, Elmar Stickeler — 2006
• Reactive oxygen species in vascular endothelial cell motility. Roles of NAD(P)H oxidase and Rac1.Suhad Bahijri, D Akbar, Raddadi R. Al — 2006
• α1β1-integrin engagement to distinct laminin-1 domains orchestrates spreading, migration and survival of neural crest cells through independent signaling pathwaysE. P. Muntz, Daniel A. Erwin, Gerald Pham-Van-Diep — 2006
• CAP interacts with cytoskeletal proteins and regulates adhesion‐mediated ERK activation and motility史朗 三輪 — 2006
• Signaling mechanisms utilized by antigen receptors and integrins: common intermediates, different outcomes?Alicia Namesny Vallespir — 2007
• Integrins, vascular remodeling, and hypertension.Jesús Vicente Chamorro — 2007
• The Regulation of Dendritic Spine Plasticity by EphB and N-methyl-D-aspartate Receptors Through Spatial Control Over Cofilin Activity in Mature Hippocampal NeuronsCrystal G. Pontrello — 2010
• Ubiquitin-mediated proteasomal degradation in normal and malignant hematopoiesis.Mélina L. Heuzé, Isabelle Lamsoul, Christel Moog‐Lutz — 2008
• Cross talk between paxillin and Rac is critical for mediation of barrier-protective effects by oxidized phospholipids.Мухин Алексей Арьевич — 2008
• The dioxin receptor regulates the constitutive expression of the vav3 proto-oncogene and modulates cell shape and adhesion.Consuelo Iranzo, Thanalí Patruyo — 2009
• Ciprofloxacin-mediated inhibition of tenocyte migration and down-regulation of focal adhesion kinase phosphorylation.Alberto Balil Illana — 2009
• Therapeutic strategies for inhibiting invasion in glioblastoma孟建平 — 2009
• uPAR/Cathepsin B Overexpression Reverse Angiogenesis by Rescuing FAK Phosphorylation in uPAR/Cathepsin B Down Regulated Meningioma尚憲 清水 — 2011
• CD73 and CD29 concurrently mediate the mechanically induced decrease of migratory capacity of mesenchymal stromal cells.José Domingo Valls Lloret — 2011
• Cancer Chemoprevention by Dietary Compounds Targeting AngiogenesisWasamon Nutakul — 2014
• ERM proteins in cancer progression恵一 伊東 — 2014

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• Tyrosine phosphorylation of paxillin, FAK, and p130CAS: effects on cell spreading and migration.Tracee S. Panetti — 2002
• JNK Acts at Focal Adhesions2003
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• Gene Regulation by Adhesion-dependent Signal Transduction PathwaysJill K. Slack — 2002
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