Steroid receptor coactivator-3, a homolog of Taiman that controls cell migration in the Drosophila ovary, regulates migration of human ovarian cancer cells.
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Summary
A novel role for SRC-3 is revealed in ovarian cancer progression by promoting cell migration, independently of its role in estrogen receptor signaling.
- Type
- article
- Published
- 2005-12-21
- Cited by
- 39
- References
- 43
- OpenAlex
- https://openalex.org/W16298470
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:19252579
Keywords
Computer science
References
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- Frequent amplification of chromosomal region 20q12-q13 in ovarian cancer.
- Activation of estrogen receptor transfected into a receptor-negative breast cancer cell line decreases the metastatic and invasive potential of the cells.
- An Isoform of the Coactivator AIB1 That Increases Hormone and Growth Factor Sensitivity Is Overexpressed in Breast Cancer*
- Whole genome expression profiling of advance stage papillary serous ovarian cancer reveals activated pathways
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- Nuclear receptor coactivator ACTR is a novel histone acetyltransferase and forms a multimeric activation complex with P/CAF and CBP/p300.
- Border-cell migration: the race is on
- Ovarian Cancer Metastasis: Integrating insights from disparate model organisms
- Expression of nuclear receptor coregulators in ovarian stromal and epithelial tumours.
- Lessons from border cell migration in the Drosophila ovary: A role for myosin VI in dissemination of human ovarian cancer.
- Heterogeneity of the motility responses in malignant tumor cells: A biological basis for the diversity and homing of metastatic cells
- Genetic downregulation of pregnancy‐associated plasma protein‐A (PAPP‐A) by bikunin reduces IGF‐I‐dependent Akt and ERK1/2 activation and subsequently reduces ovarian cancer cell growth, invasion and metastasis
- Expression of RAC 3, a steroid hormone receptor co-activator in prostate cancer
- Focal adhesion kinase: in command and control of cell motility
- Myosin VI is required for E-cadherin-mediated border cell migration
- Amplification and over‐expression of the AIB1 nuclear receptor co‐activator gene in primary gastric cancers
- Gene Amplification and Expression of the Steroid Receptor Coactivator SRC3 (AIB1) in Sporadic Breast and Endometrial Carcinomas
- A Transcriptional Coactivator, Steroid Receptor Coactivator-3, Selectively Augments Steroid Receptor Transcriptional Activity*
Cited by
- Role for Growth Regulation by Estrogen in Breast Cancer 1 (GREB1) in Hormone-Dependent Cancers
- [Natural history of ovary cancer].
- Drosophila orthologues to human disease genes: an update on progress.
- Role of the PY Motif Containing Protein, WBP-2 in ER, PR Signaling and Breast Tumorigenesis
- Minireview: steroid receptor coactivator-3: a multifarious coregulator in mammary gland metastasis.
- Normal and Cancer-Related Functions of the p160 Steroid Receptor Coactivator (SRC) Family
- Immunohistochemical localization of steroid receptor coactivators in chondrosarcoma: an in vivo tissue microarray study.
- Minireview: Steroid/nuclear receptor-regulated dynamics of occluding and anchoring junctions.
- Overexpression of AIB1 correlates inversely with E-cadherin expression in pancreatic adenocarcinoma and may promote lymph node metastasis
- Overexpression of steroid receptor coactivator-3 in bone cancers: an in vivo immunohistochemical study with tissue microarray.
- SRC-3Δ4 mediates the interaction of EGFR with FAK to promote cell migration
- A PAK-activated linker for EGFR and FAK
- Steroid Receptor Coactivator-3 as a Potential Molecular Target for Cancer Therapy
- Modeling Migration and Metastasis in Drosophila
- SRC-3 Has a Role in Cancer Other Than as a Nuclear Receptor Coactivator
- Regulation of SRC-3 Intercompartmental Dynamics by Estrogen Receptor and Phosphorylation
- Steroid Receptor Coactivator-3 (SRC-3/AIB1) as a Novel Therapeutic Target in Triple Negative Breast Cancer and Its Inhibition with a Phospho-Bufalin Prodrug
- Natural history of ovarian cancer
- Ovarian Cancer: Characteristics & Management
- SRC-3: a transcriptional coactivator and therapeutic target in cancer
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