α1β1-integrin engagement to distinct laminin-1 domains orchestrates spreading, migration and survival of neural crest cells through independent signaling pathways

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Summary

Laminin-1, a major component of their migration routes, promotes crest cell spreading, migration and survival through two distinct integrin-binding domains that are situated on both sides of its α1 subunit and can be separated in the LN-1 elastase proteolytic fragments E1' and E8.

Type
review
Published
2006-08-01
Cited by
39
References
68

Keywords

Mach number, Monte Carlo method, Scattering, Physics, Shock wave

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