Specificity of the HP1 chromo domain for the methylated N‐terminus of histone H3
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Summary
In situ immunofluorescence demonstrates that methyl‐K9 H3 and HP1 co‐localize to the heterochromatic regions of Drosophila polytene chromosomes and indicates that sequence diversity in chromo domains may lead to diverse functions in eukaryotic gene regulation.
- Type
- article
- Published
- 2001-09-17
- Cited by
- 449
- References
- 47
- Access
- Open access
- OpenAlex
- https://openalex.org/W2024295388
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:9841451
Keywords
Heterochromatin protein 1, Histone H3, Biology, Isothermal titration calorimetry, Heterochromatin
References
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- The language of covalent histone modifications
- Methylation of histone H3 at lysine 4 is highly conserved and correlates with transcriptionally active nuclei in Tetrahymena.
- Acetylated histone H4 on the male X chromosome is associated with dosage compensation in Drosophila.
- Localization and phosphorylation of HP1 proteins during the cell cycle in mammalian cells
- The structural basis for the recognition of acetylated histone H4 by the bromodomain of histone acetyltransferase Gcn5p
Cited by
- Epigenetics and behavioural plasticity: drosophila euchromatin histone metiltransferase and foraging
- RNA meets chromatin.
- Human Histone Demethylase LSD1 Reads the Histone Code*
- Leaving a mark: the many footprints of the elongating RNA polymerase II.
- How to build a centromere: from centromeric and pericentromeric chromatin to kinetochore assembly.
- Remodeling of higher order chromatin structure by the JIL-1 histone H3 kinase in Drosophila
- Análisis bioinformático de los reguladores epigenéticos
- Analysis of Chromatin Structure of Genes Silenced by Heterochromatin in Trans
- BRG1 requirement for long-range interaction of a locus control region with a downstream promoter
- Untargeted tail acetylation of histones in chromatin: lessons from yeast.
- Affinity, stoichiometry and cooperativity of heterochromatin protein 1 (HP1) binding to nucleosomal arrays
- Rôle de l'ETP Corto et de la protéine ribosomique RPL12 dans la régulation transcriptionnelle chez Drosophila melanogaster
- Tackling malignant melanoma epigenetically: histone lysine methylation
- The epigenetic regulation of cell cycle and chromatin dynamic by sirtuins
- Site-specific analysis of histone methylation and acetylation.
- Regulation and function of H3K9 methylation.
- The Sounds of Silence – Histone Deacetylation Meets hisTone Methylation
- Chromatin proteins are determinants of centromere function.
- Understanding Higher Order Heterochromatin Structure And Its Determinants
- HP1/ORC Complex and Heterochromatin Assembly
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