Specificity of the HP1 chromo domain for the methylated N‐terminus of histone H3

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Summary

In situ immunofluorescence demonstrates that methyl‐K9 H3 and HP1 co‐localize to the heterochromatic regions of Drosophila polytene chromosomes and indicates that sequence diversity in chromo domains may lead to diverse functions in eukaryotic gene regulation.

Type
article
Published
2001-09-17
Cited by
449
References
47
Access
Open access

Keywords

Heterochromatin protein 1, Histone H3, Biology, Isothermal titration calorimetry, Heterochromatin

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