Diverse Ways to Control p27Kip1 Function: miRNAs Come into Play

Keywords

Biology, microRNA, Computational biology, Function (biology), Gene

References

• p27(Kip1) ubiquitination and degradation is regulated by the SCF(Skp2) complex through phosphorylated Thr187 in p27.ひとみ 加藤 — 1999
• Pten and p27KIP1 cooperate in prostate cancer tumor suppression in the mouseJane Austin — 2001
• MicroRNA genes are transcribed by RNA polymerase IIEdwin Arbey Hernández García, Diego Salazar, P. Melgarejo — 2004
• The murine gene p27Kip1 is haplo-insufficient for tumour suppressionMatthew L. Fero, Erin Randel, Kay E. Gurley — 1998
• p45SKP2 promotes p27Kip1 degradation and induces S phase in quiescent cellsHedwig Sutterlüty, Eric Chatelain, Alain Marti — 1999
• The cell-cycle regulatory protein Cks1 is required for SCFSkp2-mediated ubiquitinylation of p27Dvora Ganoth, Gil Bornstein, Tun Kiat Ko — 2001
• Are all cancer genes equal?Jiří Bártek, Jiri Lukas — 2001
• Oncogenic kinase signallingPeter Blume‐Jensen, Tony Hunter — 2001
• Regulation of the Cdk inhibitor p27 and its deregulation in cancerJoyce M. Slingerland, Michele Pagano — 2000
• Prediction of plant microRNA targets.Matthew W. Rhoades, Brenda J. Reinhart, Lee P. Lim — 2002
• Both natural and designed micro RNAs can inhibit the expression of cognate mRNAs when expressed in human cells.Yan Zeng, Eric J. Wagner, Bryan R. Cullen — 2002
• Cell Cycle Control: A Complex IssueNancy Olashaw, Tapan Bagui, W. J. Pledger — 2004
• 14-3-3 suppresses the nuclear localization of threonine 157-phosphorylated p27(Kip1).Toshihiro Sekimoto, Masahiro Fukumoto, Yoshihiro Yoneda — 2004
• The role of microRNA genes in papillary thyroid carcinoma.Huiling He, Krystian Jażdżewski, Wei Li — 2005
• c-Myc-regulated microRNAs modulate E2F1 expressionKathryn A. O’Donnell, Erik A. Wentzel, Karen Zeller — 2005
• Cytoplasmic ubiquitin ligase KPC regulates proteolysis of p27Kip1 at G1 phaseTakumi Kamura, Taichi Hara, Masaki Matsumoto — 2004
• A Role for the RNase III Enzyme DCR-1 in RNA Interference and Germ Line Development in Caenorhabditis elegansScott W. Knight, Brenda Bass — 2001
• Translational Control of p27Kip1 Accumulation During the Cell CycleLudger Hengst, Steven I. Reed — 1996
• The nuclear RNase III Drosha initiates microRNA processingYoontae Lee, Chiyoung Ahn, Jinju Han — 2003
• Cytoplasmic relocalization and inhibition of the cyclin-dependent kinase inhibitor p27Kip1 by PKB/Akt-mediated phosphorylation in breast cancerGiuseppe Viglietto, Maria Letizia Motti, Paola Bruni — 2002

Cited by

• Regulation of p27(kip1) mRNA expression by microRNAs.Richard Bruce Winders — 2010
• The transcription factor FOXM1 (Forkhead box M1): proliferation-specific expression, transcription factor function, target genes, mouse models, and normal biological roles.Ying‐Nan Chiu — 2013
• microRNAs in cancer: from bench to bedside.María Angélica Cortez, Cristina Ivan, Peng Zhou — 2010
• REGULATION OF MAMMARY GLAND DEVELOPMENT AND TUMORIGENESIS BY 14-3-3 ZETASumaiyah K. Rehman — 2014
• MicroRNA miR‐24 promotes cell proliferation by targeting the CDKs inhibitors p27Kip1 and p16INK4aSimona Giglio, Roberto Cirombella, Rachele Amodeo — 2013
• A Novel Mutation in the Upstream Open Reading Frame of the CDKN1B Gene Causes a MEN4 PhenotypeGianluca Occhi, Daniela Regazzo, Giampaolo Trivellin — 2013
• Profilin-1 overexpression inhibits proliferation of MDA-MB-231 breast cancer cells partly through p27kip1 upregulationLi Zou, Zhijie Ding, Partha Roy — 2010
• Control of cell proliferation pathways by microRNAsMaría J. Bueno, Ignacio Pérez de Castro, Marcos Malumbres — 2008
• IKK-β/NFκB p65 Mediates p27kip1 Protein Degradation in Arsenite ResponseWei Guo, Jinyi Liu, Jinlong Jian — 2014
• [p53 and p27 gene expression in subserosal gallbladder carcinoma].Iván Roa E, Soledad Lantadilla H, Gilda Ibacache S — 2009
• Pumilio turns on microRNA functionRobinson Triboulet, Richard I. Gregory — 2010
• RETRACTED ARTICLE: MIR221/MIR222-driven post-transcriptional regulation of P27KIP1 and P57KIP2 is crucial for high-glucose- and AGE-mediated vascular cell damageG. Togliatto, A. Trombetta, P. Dentelli — 2011
• Genome-wide siRNA Screen Identifies the Radiosensitizing Effect of Downregulation of MASTL and FOXM1 in NSCLCRemco Nagel, Marijke Stigter‐van Walsum, Marijke Buijze — 2015
• Long non-coding RNA UCA1 promotes breast tumor growth by suppression of p27 (Kip1)Jianguo Huang, Nanjiang Zhou, Kounosuke Watabe — 2014
• The regulatory loop of COMP1 and HNF-4-miR-150-p27 in various signaling pathwaysWeiwei Nie, Jun Gu, Zexing Wang — 2014
• p27 as Jekyll and Hyde: Regulation of cell cycle and cell motilityMichelle D. Larrea, Seth A. Wander, Joyce M. Slingerland — 2009
• miR-340 inhibits tumor cell proliferation and induces apoptosis by targeting multiple negative regulators of p27 in non-small cell lung cancerSerena Fernandez, Maurizio Risolino, Nadia Mandia — 2014
• The Cdk inhibitor p27 in human cancer: prognostic potential and relevance to anticancer therapyIsabel Chu, Ludger Hengst, Joyce M. Slingerland — 2008
• Localization‐ and mutation‐dependent microRNA (miRNA) expression signatures in gastrointestinal stromal tumours (GISTs), with a cluster of co‐expressed miRNAs located at 14q32.31Florian Haller, Anja von Heydebreck, Jitao David Zhang — 2010
• Immunohistochemical expression of p27(kip1) in metastatic laryngeal squamous cell carcinoma.Magdalena Bodnar, Łukasz Szylberg, Wojciech Kaźmierczak — 2014

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