Regulation of p27(kip1) mRNA expression by microRNAs.
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Summary
This chapter will provide an overview on the role of microRNAs in cancer, and will discuss how micro RNAs regulate p27 expression and the implications for tumor progression.
- Type
- article
- Published
- 2010-01-01
- Cited by
- 9
- References
- 79
- OpenAlex
- https://openalex.org/W19841881
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:30494460
Keywords
Frontier, Settlement (finance), History, Economic history, Economics
References
- Regulation of cyclin dependent kinase 6 by microRNA 124 in medulloblastoma
- Prognostic significance of the cell cycle inhibitor p27Kip1 in chronic B-cell lymphocytic leukemia.
- The murine gene p27Kip1 is haplo-insufficient for tumour suppression
- mir-29 regulates Mcl-1 protein expression and apoptosis
- p27(Kip1): regulation and function of a haploinsufficient tumor suppressor and its misregulation in cancer.
- Let-7 expression defines two differentiation stages of cancer
- Mechanisms of post-transcriptional regulation by microRNAs: are the answers in sight?
- Inhibition of Cdk4 Activity Enhances Translation of p27 kip1 in Quiescent Rb-negative Cells*
- Control of cell proliferation pathways by microRNAs
- Translational Control of p27Kip1 Accumulation During the Cell Cycle
- Regulation of p27Kip1 by miRNA 221/222 in Glioblastoma
- miR-15 and miR-16 induce apoptosis by targeting BCL2.
- Reduced expression of Dicer associated with poor prognosis in lung cancer patients
- High expression levels of p27 correlate with lymph node status in a subset of advanced invasive breast carcinomas
- p27Kip1 Metabolism: A Fascinating Labyrinth
- Synergistic action of the microRNA‐17 polycistron and Myc in aggressive cancer development
- Modulation of LMP1 protein expression by EBV-encoded microRNAs
- How to decrease p27Kip1 levels during tumor development.
- Diverse Ways to Control p27Kip1 Function: miRNAs Come into Play
- p27 as a target for cancer therapeutics.
Cited by
- Immunohistochemical expression of p27(kip1) in metastatic laryngeal squamous cell carcinoma.
- Tuberin and p27 expression in breast cancer patients with or without BRCA germline mutations
- Partial hepatectomy in rats results in immediate down-regulation of p27Kip1 in residual liver tissue by transcriptional and post-translational processes
- NSun2 delays replicative senescence by repressing p27 (KIP1) translation and elevating CDK1 translation
- miR-222 confers the resistance of breast cancer cells to Adriamycin through suppression of p27(kip1) expression.
- MicroRNAs in parathyroid physiopathology.
- MiR-222 promotes the progression of polycystic ovary syndrome by targeting p27 Kip1.
- An Unanticipated Modulation of Cyclin-Dependent Kinase Inhibitors: The Role of Long Non-Coding RNAs
- Exploiting Cell Cycle Pathways in Cancer Therapy: New (and Old) Targets and Potential Strategies
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